Evidence map›Paper›PMID 31145826›Full record

ArticleClinical pharmacology and therapeutics2019

Applying Multiplex Assays to Understand Variation in Pharmacogenes.

Melissa Chiasson, Maitreya J Dunham, Allan E Rettie, Douglas M Fowler

Abstract read
In one paragraph

Article in Clinical pharmacology and therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Bioinformatics advances · 2026
    Article
  2. Review
  3. Structural and energetic analysis of stabilizing indel mutations.bioRxiv : the preprint server for biology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Pharmacogenetics: Chasing Perfection.Clinical pharmacology and therapeutics · 2019
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melissa ChiassonDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.
Maitreya J DunhamDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-9944-2666
Allan E RettieDepartment of Medicinal Chemistry, University of Washington, Seattle, Washington, USA.
Douglas M FowlerDepartment of Genome Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-7614-1713

Funding

Vitamin K gene network: Variant discovery and characterizationP01GM116691 · NIGMS · UNIVERSITY OF WASHINGTON · PI THUMMEL, KENNETH E. · 2016 to 2020
$7.6M
Large-Scale Methods for Assessing the Consequences of Mutations in ProteinsR01GM109110 · NIGMS · UNIVERSITY OF WASHINGTON · PI FOWLER, DOUGLAS M · 2014 to 2021
$2.4M
F-CAP: Functionalization of Variants in Clinically Actionable PharmacogenesR24GM115277 · NIGMS · UNIVERSITY OF WASHINGTON · PI FOWLER, DOUGLAS M, RETTIE, ALLAN EDWARD · 2015 to 2017
$2.2M
Comprehensive, context-aware, functional analysis of Cytochrome P450 variantsR01GM132162 · NIGMS · UNIVERSITY OF WASHINGTON · PI DUNHAM, MAITREYA J, FOWLER, DOUGLAS M · 2019 to 2022
$2.1M
Howard Hughes Medical InstituteNIGMS NIH HHS P01 GM116691NIGMS NIH HHS R01 GM109110NIGMS NIH HHS R01 GM132162NIGMS NIH HHS R24 GM115277
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

High-Throughput Nucleotide SequencingHumansMultiplex Polymerase Chain ReactionPharmacogeneticsPharmacogenomic VariantsPrecision MedicineProcedures and Techniques UtilizationSensitivity and SpecificitySequence Analysis, DNA

Identifiers

PMID31145826
PMCPMC6663607

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.