Evidence map›Paper›PMID 31145711›Full record

ArticleJournal of hypertension2019

Prevalence of ambulatory blood pressure phenotypes using the 2017 American College of Cardiology/American Heart Association blood pressure guideline thresholds: data from the Coronary Artery Risk Development in Young Adults study.

Bharat Poudel, John N Booth, Swati Sakhuja, Andrew E Moran, Joseph E Schwartz, Donald M Lloyd-Jones, Cora E Lewis, James M Shikany, Daichi Shimbo, Paul Muntner

Abstract read
In one paragraph

Article in Journal of hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Brazilian Guidelines of Hypertension - 2025.Arquivos brasileiros de cardiologia · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bharat PoudelUniversity of Alabama at Birmingham, Birmingham, Alabama.
John N BoothUniversity of Alabama at Birmingham, Birmingham, Alabama.
Swati SakhujaUniversity of Alabama at Birmingham, Birmingham, Alabama.
Andrew E MoranColumbia University, New York.
Joseph E SchwartzColumbia University, New York.
Donald M Lloyd-JonesNorthwestern University, Chicago, Illinois, USA.
Cora E LewisUniversity of Alabama at Birmingham, Birmingham, Alabama.
James M ShikanyUniversity of Alabama at Birmingham, Birmingham, Alabama.
Daichi ShimboColumbia University, New York.
Paul MuntnerUniversity of Alabama at Birmingham, Birmingham, Alabama.

Funding

Midcareer Investigator Award in Patient-Oriented Research in Human HypertensionK24HL125704 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2015 to 2019
$573k
CORONARY ARTERY DISEASE RISK DEVELOPMENT IN YOUNG ADULTS-N01HC95095-268095095N01HC095095 · HC · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAMS, DALE · 1989 to 2006
$376k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048050 · HC · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 1985 to 2000
$102k
STUDY CORONARY HEART DISEASE RISK IN YOUNG ADULTSN01HC048048 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHREINER, PAMELA J · 1985 to 2000
$53k
NHLBI NIH HHS HHSN268201300027CNHLBI NIH HHS HHSN268201800003INHLBI NIH HHS HHSN268201800004INHLBI NIH HHS HHSN268201800005INHLBI NIH HHS HHSN268201800006INHLBI NIH HHS HHSN268201800007INHLBI NIH HHS K24 HL125704NHLBI NIH HHS N01 HC048048NHLBI NIH HHS N01 HC048050NHLBI NIH HHS N01 HC095095
6 · The paper itself

Abstract

backgroundThe 2017 American College of Cardiology/American Heart Association (ACC/AHA) blood pressure (BP) guideline lowered the BP thresholds for defining hypertension compared with the Seventh Report of the Joint National Committee (JNC7) guideline.

methodsWe analyzed clinic and ambulatory BP monitoring data from 717 Coronary Artery Risk Development in Young Adults study participants and compared the prevalence of clinic and out-of-clinic BP phenotypes using thresholds from the 2017 ACC/AHA and JNC7 guidelines.

resultsAmong participants not taking antihypertensive medication and according to the JNC7 and 2017 ACC/AHA guidelines, 11.1 and 30.1% of participants had clinic hypertension, 37.5 and 57.9% had awake hypertension, 35.7 and 58.1% had asleep hypertension, and 35.7 and 58.6% had 24-h hypertension, respectively. According to the JNC7 and 2017 ACC/AHA guideline definitions, 1.9 and 3.2% had white-coat hypertension, 28.2 and 31.0% had masked hypertension and 9.3 and 26.9% had sustained hypertension, respectively. Among participants taking antihypertensive medication and when defined using the JNC7 and 2017 ACC/AHA guideline BP thresholds, 18.6 and 45.3% had uncontrolled clinic BP, 48.1 and 62.5% had uncontrolled awake BP, 48.1 and 70.2% had uncontrolled asleep BP and, 47.7 and 65.3% had uncontrolled 24-h BP, respectively. Using JNC7 and 2017 ACC/AHA guideline BP thresholds, the prevalence was 1.4 and 5.2% for white-coat effect, 30.9 and 22.5% for masked uncontrolled hypertension, and 17.2 and 40.0% for sustained uncontrolled BP, respectively.

conclusionThe 2017 ACC/AHA guideline results in a substantially higher prevalence of awake, asleep, 24-h, and sustained hypertension.

Indexed as

AdolescentAdultAmerican Heart AssociationBlood PressureBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryCardiologyFemaleHumansHypertensionMaleMasked HypertensionPhenotypePractice Guidelines as TopicPrevalenceUnited States

Identifiers

PMID31145711
PMCPMC10761214

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.