Evidence map›Paper›PMID 31145549›Full record

Observational studyJournal of digestive diseases2019

Influence of serum vitamin D level on Helicobacter pylori eradication: A multi-center, observational, prospective and cohort study.

Chuan Han, Zhen Ni, Ting Yuan, Jian Zhang, Chan Wang, Xin Wang, Han Bing Ning, Jie Liu, Nina Sun, Cai Fang Liu and 3 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of digestive diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Vitamins andFrontiers in nutrition · 2021
    Pooled it
  2. Review
  3. Connection of vitamin D levels in blood serum withPrzeglad gastroenterologiczny · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. The synergistic effect ofFrontiers in cellular and infection microbiology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Factors Affect the Eradication Rate ofInfection and drug resistance · 2022
    Article
  12. The Effects of Vitamins and Micronutrients onJournal of immunology research · 2022
    Review
  13. Vitamin D3 is well Correlated with Anti-Advanced biomedical research · 2022
    Article
  14. Review
  15. Article
  16. Association ofThe American journal of tropical medicine and hygiene · 2020
    Article
  17. Review
  18. Review
  19. Observational
  20. Authors' reply.Annals of gastroenterology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chuan HanState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, Shaanxi Province, China.ORCID https://orcid.org/0000-0002-0330-1082
Zhen NiState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, Shaanxi Province, China.
Ting YuanState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, Shaanxi Province, China.
Jian ZhangState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, Shaanxi Province, China.
Chan WangDepartment of Gastroenterology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi Province, China.
Xin WangDepartment of Gastroenterology, Xianyang Central Hospital, Xianyang, Shaanxi Province, China.
Han Bing NingDepartment of Gastroenterology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Jie LiuState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, Shaanxi Province, China.
Nina SunXi'an Medical University, Xi'an, Shaanxi Province, China.
Cai Fang LiuXi'an Medical University, Xi'an, Shaanxi Province, China.
Miao ShiXi'an Medical University, Xi'an, Shaanxi Province, China.
Wen Quan LuDepartment of Gastroenterology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Yong Quan ShiState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, Shaanxi Province, China.ORCID https://orcid.org/0000-0001-9515-7577

Funding

National Natural Science Foundation of China 81470805National Natural Science Foundation of China 81873554Shaanxi Science and Technology Innovation Team Project 2018TD-003
6 · The paper itself

Abstract

objectivesThis study was designed to test whether serum vitamin D levels affected Helicobacter pylori (H. pylori) infection and eradication rates.

methodsA multicenter observational prospective cohort study was conducted. A total of 496 H. pylori

resultsSerum vitamin D levels were significantly lower in the H. pylori

conclusionsSerum vitamin D level may affect H. pylori infection and its eradication. Randomized controlled trials are needed to find out whether vitamin D supplements may increase the H. pylori eradication rate.

Indexed as

Helicobacter pyloriAdultAntacidsAnti-Bacterial AgentsBismuthBreath TestsDrug Therapy, CombinationFemaleHelicobacter InfectionsHumansMaleMiddle AgedProspective StudiesTreatment OutcomeUreaVitamin DAntacidsAnti-Bacterial AgentsBismuthUreaVitamin DeradicationHelicobacter pyloriinfectionvitamin D

Identifiers

PMID31145549
PMCPMC6851741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.