ArticleJournal of diabetes investigation2020
Triglyceride to high-density lipoprotein cholesterol ratio is associated with incident diabetes in men: A retrospective study of Chinese individuals.
Article in Journal of diabetes investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Hypertriglyceridemia is a dose-dependent risk factor for type 2 diabetes mellitus: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Association between triglyceride to high-density lipoprotein cholesterol ratio and new-onset diabetes mellitus.Archives of endocrinology and metabolism · 2026Article
- Association between the triglyceride to high-density lipoprotein cholesterol ratio and type 2 diabetes mellitus in non-alcoholic fatty liver disease.Scientific reports · 2024Article
- Article
- Non-linear relationship between pulse pressure and the risk of pre-diabetes: a secondary retrospective Chinese cohort study.BMJ open · 2024Article
- Exposure to ambient air pollutants, serum miRNA networks, lipid metabolism, and non-alcoholic fatty liver disease in young adults.Ecotoxicology and environmental safety · 2023Article
- Effect of circulating ceramides on adiposity and insulin resistance in patients with type 2 diabetes: An observational cross-sectional study.Endocrinology, diabetes & metabolism · 2023Observational
- The correlation of triglyceride/high-density lipoprotein cholesterol ratio with muscle mass in type 2 diabetes patients.BMC endocrine disorders · 2023Article
- The association between fatty liver index and onset of diabetes: secondary analysis of a population-based cohort study.BMC public health · 2023Article
- Association between triglyceride to high-density lipoprotein cholesterol ratio and type 2 diabetes risk in Japanese.Scientific reports · 2023Article
- Association of four lipid-derived indicators with the risk of developing type 2 diabetes: a Chinese population-based cohort study.Lipids in health and disease · 2023Article
- Type 2 Diabetes Related Mitochondrial Defects in Peripheral Mononucleated Blood Cells from Overweight Postmenopausal Women.Biomedicines · 2023Article
- Association between the triglyceride to high-density lipoprotein cholesterol ratio and the risk of gestational diabetes mellitus: a second analysis based on data from a prospective cohort study.Frontiers in endocrinology · 2023Article
- Article
- Association between hemoglobin and chronic kidney disease progression: a secondary analysis of a prospective cohort study in Japanese patients.BMC nephrology · 2022Article
- Nonlinear association between changes in fasting plasma glucose and the incidence of diabetes in a nondiabetic Chinese cohort.BMC endocrine disorders · 2022Article
- Establishment and validation of a nomogram that predicts the risk of type 2 diabetes in obese patients with non-alcoholic fatty liver disease: a longitudinal observational study.American journal of translational research · 2022Article
- The Association Between Congestive Heart Failure and One-Year Mortality After Surgery in Singaporean Adults: A Secondary Retrospective Cohort Study Using Propensity-Score Matching, Propensity Adjustment, and Propensity-Based Weighting.Frontiers in cardiovascular medicine · 2022Article
- The Role of Changes in Cumulative Lipid Parameter Burden in the Pathogenesis of Type 2 Diabetes Mellitus: A Cohort Study of People Aged 35-65 Years in Rural China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- IoT-Based Hybrid Ensemble Machine Learning Model for Efficient Diabetes Mellitus Prediction.Computational intelligence and neuroscience · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AIMS/
introductionDyslipidemia is commonly present in type 2 diabetes mellitus patients. Recently, the triglyceride : high-density lipoprotein cholesterol (TG/HDL-C) ratio, a novel parameter of lipid abnormality, has been seen as an independent predictor for incident diabetes. However, the correlation of the TG/HDL-C ratio with incident diabetes in the Chinese population and how this relationship is impacted by sex have been rarely studied. In the present study, the correlation of the TG/HDL-C ratio with incident diabetes is investigated between different sexes of the Chinese population. MATERIALS AND
methodsA total of 116,855 participants who were free of diabetes at baseline were enrolled in the study. The participants were grouped by the median value (0.82) of the TG/HDL-C ratio. Then, participants were further analyzed according to their sex. Cumulative incidence and person-years incidence were used to express the incidence rate. The predictive value of the TG/HDL-C ratio for incident diabetes was probed by the Cox regression proportional hazards model.
resultsThe mean age of the participants was 44.1 ± 12.9 years, and 53% of participants (n = 62,868) were the men. A total of 2,685 incident diabetes cases occurred during the 3.1 years of the median follow-up period. The cumulative incidence in total incident diabetes patients, men and women was 2.30% (2.21-2.38%), 3.01% (2.87-3.14%) and 1.47% (1.37-1.57%), respectively. After the adjustment of multivariate factors, the multivariate Cox regression analysis results showed that a higher TG/HDL-C ratio was the independent predictive factor of incident diabetes in men (hazard ratio 1.30, 95% confidence interval 1.03-1.64), compared with women (hazard ratio 0.85, 95% confidence interval 0.53-1.38).
conclusionsAmong the Chinese population, the TG/HDL-C ratio is an independent predictor for incident diabetes in male patients.
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