ArticleJournal of diabetes investigation2020
Comparing treatment intensification and clinical outcomes of metformin and dipeptidyl peptidase-4 inhibitors in treatment-naïve patients with type 2 diabetes in Japan.
Article in Journal of diabetes investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Article
- Adherence and treatment discontinuation of oral semaglutide and once-weekly semaglutide injection at 12 month follow-up: Japanese real-world data.Journal of diabetes investigation · 2024Observational
- Article
- A consensus statement from the Japan Diabetes Society: A proposed algorithm for pharmacotherapy in people with type 2 diabetes - 2nd edition (English version).Journal of diabetes investigation · 2024Article
- A consensus statement from the Japan Diabetes Society (JDS): a proposed algorithm for pharmacotherapy in people with type 2 diabetes-2nd Edition (English version).Diabetology international · 2024Article
- A consensus statement from the Japan Diabetes Society: A proposed algorithm for pharmacotherapy in people with type 2 diabetes.Journal of diabetes investigation · 2023Article
- A consensus statement from the Japan Diabetes Society (JDS): a proposed algorithm for pharmacotherapy in people with type 2 diabetes.Diabetology international · 2023Article
- Effect of Dipeptidyl Peptidase-4 Inhibitors vs. Metformin on Major Cardiovascular Events Using Spontaneous Reporting System and Real-World Database Study.Journal of clinical medicine · 2022Article
- Retrospective nationwide study on the trends in first-line antidiabetic medication for patients with type 2 diabetes in Japan.Journal of diabetes investigation · 2022Article
- Dose distribution and up-titration patterns of metformin monotherapy in patients with type 2 diabetes.Endocrinology, diabetes & metabolism · 2020Article
- Comparing treatment intensification and clinical outcomes of metformin and dipeptidyl peptidase-4 inhibitors in treatment-naïve patients with type 2 diabetes in Japan.Journal of diabetes investigation · 2020Article
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4 authors.
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Abstract
Japan's guidelines emphasize tailored therapy, but do not guide physicians on the use of a specific regimen in drug-naive patients. The role of long-term initial therapy could be important in key elements of diabetes treatment, such as continuation of the initially prescribed drug. We investigated the frequency of occurrence to treatment intensification after the initiation of metformin or dipeptidyl peptidase-4 inhibitor treatment. In multivariable-adjusted Cox proportional hazards models, initiation of dipeptidyl peptidase-4 inhibitor was associated with a low hazard of intensification. The findings of this survey showed that dipeptidyl peptidase-4 inhibitors were the preferred first-line treatment in Japan because of the high continuation rate of the treatment and hemoglobin A1c-lowering effect. This information would provide guidance in selecting initial hypoglycemic drugs to optimize the treatment of type 2 diabetes mellitus patients in Japan and Asia.
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