ReviewWiley interdisciplinary reviews. RNA2019
mRNA methylation in cell senescence.
Review in Wiley interdisciplinary reviews. RNA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 85 citations in OpenAlex.
- RNA modifications in health and disease: from mechanistic insights to therapeutic applications.Precision clinical medicine · 2025Review
- RNA Modifications in Health and Disease.MedComm · 2025Review
- Decreased FTO Expression Promotes Ovarian Granulosa Cells Aging.Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- RNA m6A methylation regulatory mechanism of resveratrol in premature senescence cells.Food science & nutrition · 2024Article
- A transcriptomic analysis of dental pulp stem cell senescence in vitro.Biomedical engineering online · 2024Article
- Cellular Senescence-Related Long Non-coding RNA Signatures Predict Prognosis in Juvenile Osteosarcoma.Phenomics (Cham, Switzerland) · 2024Article
- Increased PTCHD4 expression via m6A modification of PTCHD4 mRNA promotes senescent cell survival.Nucleic acids research · 2024Article
- N6-Methyladenosine Methylation of mRNA in Cell Apoptosis.Molecular neurobiology · 2024Review
- Trimethylamine-N-oxide promotes osteoclast differentiation and oxidative stress by activating NF-κB pathway.Aging · 2024Article
- Retinoic Acid Upregulates METTL14 Expression and the mInternational journal of molecular sciences · 2024Article
- Crosstalk between m6A modification and autophagy in cancer.Cell & bioscience · 2024Review
- Establishment of a prognostic model based on mJournal of cancer research and clinical oncology · 2023Article
- Deciphering RNA mAging cell · 2023Review
- Trimethylamine N-oxide: role in cell senescence and age-related diseases.European journal of nutrition · 2023Review
- Longevity, Centenarians and Modified Cellular Proteodynamics.International journal of molecular sciences · 2023Review
- N6-Methyladenosine Methylation of mRNA in Cell Senescence.Cellular and molecular neurobiology · 2023Review
- Epigenetic control of plant senescence and cell death and its application in crop improvement.Frontiers in plant science · 2023Review
- The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence.Antioxidants (Basel, Switzerland) · 2022Review
- Transcriptome-wide N6-methyladenine methylation in granulosa cells of women with decreased ovarian reserve.BMC genomics · 2022Article
- Roles of RNA Modifications in Diverse Cellular Functions.Frontiers in cell and developmental biology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Cellular senescence, a developmental program central to normal aging and aging pathologies, is robustly regulated at the post-transcriptional level. This regulation involves the interaction of RNA-binding proteins and noncoding RNAs with senescence-associated messenger RNAs (mRNAs). There is increasing evidence that these associations are modulated by chemical modifications of specific mRNA nucleotides which can enhance or reduce the binding of regulatory factors. Recent technological advances in mass spectrometry, next-generation sequencing, and genome mapping have improved markedly the detection of mRNA modifications. Given the rising interest in the epitranscriptomic control of gene expression in aging, we discuss our incipient understanding of the chemical mRNA modifications, specifically m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.