Evidence map›Paper›PMID 31144406›Full record

ArticleCancer science2019

Carcinogen-induced tumors in SFN-transgenic mice harbor a characteristic mutation spectrum of human lung adenocarcinoma.

Yunjung Kim, Aya Shiba-Ishii, Karina Ramirez, Masafumi Muratani, Noriaki Sakamoto, Tatsuo Iijima, Masayuki Noguchi

Open access · goldAbstract read
In one paragraph

Article in Cancer science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Oxysterols Modify NLRP2 in Epithelial Cells, Identifying a Mediator of Ozone-induced Inflammation.American journal of respiratory cell and molecular biology · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yunjung KimDepartment of Pathology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Aya Shiba-IshiiDepartment of Pathology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID https://orcid.org/0000-0001-6639-4135
Karina RamirezPh.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Tsukuba, Japan.
Masafumi MurataniDepartment of Genome Biology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Noriaki SakamotoDepartment of Pathology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Tatsuo IijimaDepartment of Pathology, Ibaraki Prefectural Central Hospital, Kasama, Japan.
Masayuki NoguchiDepartment of Pathology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
University of Tsukuba · JPIbaraki Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The landscape of genetic alterations in disease models such as transgenic mice or mice with carcinogen-induced tumors has provided a huge amount of information that has shed light on the process of tumorigenesis in human non-small-cell lung cancer (NSCLC). We have previously identified stratifin (SFN) as a potent oncogene, and generated SFN-transgenic (Tg-SPC-SFN

Indexed as

14-3-3 ProteinsA549 CellsAdenocarcinoma of LungAnimalsApoptosisBiomarkers, TumorCarcinogensCarcinoma, Non-Small-Cell LungCell Line, TumorExome SequencingExoribonucleasesFemaleGene Expression Regulation, NeoplasticHumansLung NeoplasmsMale14-3-3 ProteinsBiomarkers, TumorCarcinogensExoribonucleasesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSFN protein, humanlung adenocarcinomamutational signaturenicotine-derived nitrosaminoketonestratifintransgenic mice

Identifiers

PMID31144406
PMCPMC6676126
OpenAlexW2947971196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.