Evidence map›Paper›PMID 31144277›Full record

ArticleJournal of general internal medicine2019

The Impact of Breast Density Notification Laws on Supplemental Breast Imaging and Breast Biopsy.

Loren Saulsberry, Lydia E Pace, Nancy L Keating

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Review
  13. Breast Cancer Screening Trials: Endpoints and Overdiagnosis.Journal of the National Cancer Institute · 2021
    Article
  14. Review
  15. Article
  16. Dense Breast Notification Legislation: More Reasons for Caution.Journal of general internal medicine · 2020
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Loren SaulsberryDepartment of Public Health Sciences, The University of Chicago, Chicago, IL, USA.
Lydia E PaceDivision of Women's Health, Brigham and Women's Hospital, Boston, MA, USA.
Nancy L KeatingDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA. keating@hcp.med.harvard.edu.

Funding

Program in Cancer Research Outcomes Training (PCORT)R25CA092203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI GAZELLE, G SCOTT · 2002 to 2016
$8.2M
Training in Oncology Population Sciences (TOPS)T32CA092203 · NCI · DANA-FARBER CANCER INST · PI Nancy L Keating, JENNIFER W MACK · 2018 to 2026
$3.7M
Evaluating breast cancer care in rural RwandaK07CA215819 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI PACE, LYDIA · 2018 to 2023
$1.0M
Behavioral Economics and Improving Chemotherapy Decisions for Advanced CancerK24CA181510 · NCI · HARVARD MEDICAL SCHOOL · PI KEATING, NANCY L · 2014 to 2018
$867k
NCI NIH HHS K07 CA215819NCI NIH HHS K24 CA181510NCI NIH HHS R25 CA092203NCI NIH HHS T32 CA092203
6 · The paper itself

Abstract

backgroundDense breast tissue increases breast cancer risk and lowers mammography sensitivity, but the value of supplemental imaging for dense breasts remains uncertain. Since 2009, 37 states and Washington DC have passed legislation requiring patient notification about breast density.

objectiveExamine the effects of state breast density notification laws on use of supplemental breast imaging and breast biopsies.

designDifference-in-differences analysis of supplemental imaging and biopsies before and after notification laws in 12 states enacting breast density notification laws from 2009 to 2014 and 12 matched control states. Supplemental imaging/biopsy within 6 months following an index mammogram were evaluated during four time periods related to legislation: (1) 6 months before, (2) 0-6 months after, (3) 6-12 months after, and (4) 12-18 months after.

participantsWomen ages 40-64 years receiving an initial mammogram in a state that passed a breast density notification law or a control state.

interventionMandatory breast density notification following an index mammogram. MAIN MEASURES: Use of breast biopsies and supplemental breast imaging (breast ultrasound, tomosynthesis, magnetic resonance imaging, scintimammography, and thermography), overall and by specific test. KEY

resultsSupplemental breast imaging and biopsy increased modestly in states with notification laws and changed minimally in control states. Adjusted rates of supplemental imaging and biopsy within 6 months of mammography before legislation were 8.5% and 3.1%, respectively. Compared with pre-legislation in intervention and control states, legislation was associated with adjusted difference-in-differences estimates of + 1.3% (p < 0.0001) and + 0.4% (p < 0.0001) for supplemental imaging and biopsies, respectively, in the 6-12 months after the law and difference-in-differences estimates of + 3.3% (p < 0.0001) and + 0.8% (p < 0.0001) for supplemental imaging and biopsies, respectively, 12-18 months after the law.

conclusionsAs breast density notification laws are considered, policymakers and clinicians should expect increases in breast imaging/biopsies. Additional research is needed on these laws' effects on cost and patient outcomes.

Indexed as

Breast DensityLegislation, MedicalAdultBiopsyBreast NeoplasmsFemaleHumansMammographyMiddle AgedUltrasonography, MammaryUnited Statesbreast cancercancer screeninghealth communicationhealth policyhealth services research

Identifiers

PMID31144277
PMCPMC6667574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.