ArticleEuropean radiology experimental2019
Quantification of liver fibrosis: extracellular volume fraction using an MRI bolus-only technique in a rat animal model.
Article in European radiology experimental, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- T1 Mapping-Derived Extracellular Volume Fraction for Non-Invasive Assessment of Tumor-Stroma Ratio in Rectal Cancer.Abdominal radiology (New York) · 2026Article
- Article
- Significantly elevated hepatic extracellular volume in adult patients with a Fontan circulation and its correlation with impaired functional capacity.The international journal of cardiovascular imaging · 2024Article
- Biased Quantification of Rat Liver Fibrosis-Meta-Analysis with Practical Recommendations and Clinical Implications.Journal of clinical medicine · 2023Article
- Role of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameters and Extracellular Volume Fraction as Predictors of Lung Cancer Subtypes and Lymph Node Status in Non-Small-Cell Lung Cancer Patients.Journal of Cancer · 2023Article
- Assessment of liver cirrhosis severity with extracellular volume fraction MRI.Scientific reports · 2022Article
- Efficacy Analysis of Double-Low Dynamic Contrast-Enhanced CT and Hepatic Extracellular Volume Fraction in the Diagnosis of Liver Fibrosis.Contrast media & molecular imaging · 2022Article
- Therapeutic and diagnostic targeting of fibrosis in metabolic, proliferative and viral disorders.Advanced drug delivery reviews · 2021Review
- Magnetic resonance parametric mapping of the spleen for non-invasive assessment of portal hypertension.European radiology · 2021Article
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Authors and funding
12 authors.
Funding
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Abstract
backgroundTo determine the utility of single-contrast-bolus hepatic extracellular volume (ECV) fraction measurement at different time points to detect and quantify hepatic fibrosis.
methodsDifferent grades of liver fibrosis were induced in 23 male Sprague-Dawley rats by carbon-tetrachloride (CCl
resultsFor the 8-week-CCl
conclusionsHepatic ECV obtained using a single-contrast-bolus technique can be measured 5, 15, and 25 min after injection, obtaining constant values over time, each of them being suitable to detect diffuse hepatic fibrosis. In clinical practice, post-contrast T1 relaxation times for liver ECV fraction determination might be obtained at only one time point.
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