Evidence map›Paper›PMID 31144131›Full record

ArticleAIDS and behavior2021

Evidence for the Model of Gender Affirmation: The Role of Gender Affirmation and Healthcare Empowerment in Viral Suppression Among Transgender Women of Color Living with HIV.

Jae Sevelius, Deepalika Chakravarty, Torsten B Neilands, JoAnne Keatley, Starley B Shade, Mallory O Johnson, Greg Rebchook, HRSA SPNS Transgender Women of Color Study Group

Open access · bronzeAbstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 88 citations in OpenAlex.

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  3. Adapting and Implementing an Evidence-Based Reentry Intervention for Incarcerated Transgender Women: Lessons Learned.Journal of correctional health care : the official journal of the National Commission on Correctional Health Care · 2023
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  13. HIV Self-Test Experiences and Implementation Considerations Among Transgender Women in the Philippines: Getting Ready for Scale-Up.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jae SeveliusDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, UCSF, University of California, 550 16th Street, 3rd Floor, UCSF Box 0886, San Francisco, CA, 94158, USA. jae.sevelius@ucsf.edu.ORCID http://orcid.org/0000-0002-8318-038X
Deepalika ChakravartyDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, UCSF, University of California, 550 16th Street, 3rd Floor, UCSF Box 0886, San Francisco, CA, 94158, USA.
Torsten B NeilandsDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, UCSF, University of California, 550 16th Street, 3rd Floor, UCSF Box 0886, San Francisco, CA, 94158, USA.
JoAnne KeatleyDepartment of Medicine, Center of Excellence for Transgender Health, University of California, San Francisco, CA, USA.
Starley B ShadeDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, UCSF, University of California, 550 16th Street, 3rd Floor, UCSF Box 0886, San Francisco, CA, 94158, USA.
Mallory O JohnsonDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, UCSF, University of California, 550 16th Street, 3rd Floor, UCSF Box 0886, San Francisco, CA, 94158, USA.
Greg RebchookDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, UCSF, University of California, 550 16th Street, 3rd Floor, UCSF Box 0886, San Francisco, CA, 94158, USA.
HRSA SPNS Transgender Women of Color Study Group
University of California, San Francisco · USSan Francisco AIDS Foundation · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
Mentoring and Empowerment in the Context of HIV Care for At-Risk PopulationsK24DA037034 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2014 to 2018
$918k
Mentoring clinical investigators in patient-oriented research on substance use and HIVK24DA051328 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEVELIUS, JAE M. · 2020 to 2024
$771k
HRSA U90HA24973NIDA NIH HHS K24 DA037034NIDA NIH HHS K24DA037034NIDA NIH HHS K24 DA051328NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

Transgender women of color are disproportionately impacted by HIV, poor health outcomes, and transgender-related discrimination (TD). We tested the Model of Gender Affirmation (GA) to identify intervention-amenable targets to enhance viral suppression (VS) using data from 858 transgender women of color living with HIV (49% Latina, 42% Black; 36% virally suppressed) in a serial mediation model. Global fit statistics demonstrated good model fit; statistically significant (p ≤ 0.05) direct pathways were between TD and GA, GA and healthcare empowerment (HCE), and HCE and VS. Significant indirect pathways were from TD to VS via GA and HCE (p = 0.036) and GA to VS via HCE (p = 0.028). Gender affirmation and healthcare empowerment significantly and fully mediated the total effect of transgender-related discrimination on viral suppression. These data provide empirical evidence for the Model of Gender Affirmation. Interventions that boost gender affirmation and healthcare empowerment may improve viral suppression among transgender women of color living with HIV.

Indexed as

HIV InfectionsTransgender PersonsBlack or African AmericanDelivery of Health CareFemaleGender IdentityHispanic or LatinoHumansMaleGender affirmationHealthcare empowermentHIVTransgenderViral suppression

Identifiers

PMID31144131
PMCPMC9351439
OpenAlexW2947421472

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.