ArticleEuropean radiology2019
Shear-wave elastography: role in clinically significant prostate cancer with false-negative magnetic resonance imaging.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Application of mean maximum Young's modulus value as a new parameter for differential diagnosis of prostate diseases.Scientific reports · 2025Article
- Integrating shear wave elastography and multiparametric MRI for accurate prostate cancer diagnosis.American journal of cancer research · 2025Article
- Research on the mean maximum Young's modulus value as a new diagnostic parameter for prostate cancer.Scientific reports · 2024Article
- Review
- Recent advances of multimoda ultrasound in image-guided prostate-targeted biopsy.Journal of interventional medicine · 2022Article
- [Sonography of the prostate : Relevance for urologists in daily clinical routine].Der Urologe. Ausg. A · 2022Review
- Advanced ultrasound in the diagnosis of prostate cancer.World journal of urology · 2021Article
- Characterisation of Prostate Lesions Using Transrectal Shear Wave Elastography (SWE) Ultrasound Imaging: A Systematic Review.Cancers · 2021Review
- A Nomogram Based on a Multiparametric Ultrasound Radiomics Model for Discrimination Between Malignant and Benign Prostate Lesions.Frontiers in oncology · 2021Article
- Influence of epidemiological characteristics (age, parity and other factors) in the assessment of healthy uterine cervical stiffness evaluated through shear wave elastography as a prior step to its use in uterine cervical pathology.Archives of gynecology and obstetrics · 2020Article
- The effect of regions-of-interest and elasticity modulus selection on differentiating benign and malignant cervical lymph nodes with shear wave elastography.Clinics (Sao Paulo, Brazil) · 2020Article
- Multiparametric ultrasound of prostate: role in prostate cancer diagnosis.Therapeutic advances in urologyReview
- Added value of shear-wave elastography in the prediction of extracapsular extension and seminal vesicle invasion before radical prostatectomy.Asian journal of andrologyArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo analyze the diagnostic value of adding SWE to MRI for the diagnosis of clinically significant prostate cancer with false-negative MRI results.
methodsThis was a retrospective study of 367 patients who underwent MRI, SWE, and prostate biopsy between March 2016 and November 2018 at the Shanghai Tenth People's Hospital. Serum prostate-specific antigen (PSA) and free PSA (fPSA) were measured preoperatively. Diagnostic value and accuracy was determined for MRI alone and MRI + SWE using the receiver operator characteristic curve (ROC) analysis.
resultsMRI misdiagnosed 17.9% (21/117) clinically significant prostate cancers, including 15 lesions in the peripheral zone and 6 in the central zone. Both qualitative and quantitative SWE could help detect 66.7% (10/15) significant prostate cancers with false-negative MRI, but there was no association with the Gleason score (p > 0.05). When considering the sextant of the peripheral zone, a significant association was not seen with histopathology in qualitative SWE (p = 0.071) and quantitative SWE (p = 0.598). Among age, PSA, fPSA, volume of the prostate gland, fPSA/PSA, and PSAD, only PSAD (p = 0.019) was associated with SWE results in patients with negative MRI.
conclusionsAdding SWE to MRI in patients with negative MRI for prostate examination could allow the correct diagnosis of additional patients and reduce the false-negative rate. KEY POINTS: • MRI plays an important role in clinically significant prostate cancers diagnosis. • SWE plays an important role in clinically significant prostate cancers with negative MRI. • Adding SWE to MRI in patients with negative MRI for prostate examination could allow the correct diagnosis of additional patients and reduce the false-negative rate.
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