Evidence map›Paper›PMID 31143781›Full record

ReviewJournal of immunology research2019

Novel Immune Microlens Imaging for Detection of Antigen and Antibody.

Jiahui Liang, Xiaotian Ye, Jiang He, Jing Liu, Yaoxiong Huang, Feiyue Xing

Abstract readReview
In one paragraph

Review in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiahui LiangInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou 510632, China.
Xiaotian YeInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou 510632, China.
Jiang HeDepartment of Biomedical Engineering, Jinan University, Guangzhou 510632, China.
Jing LiuSchool of Stomatology, Jinan University, Guangzhou 510632, China.
Yaoxiong HuangDepartment of Biomedical Engineering, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-9376-053X
Feiyue XingInstitute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou 510632, China.ORCID 0000-0003-0014-3565

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection and analysis of antigen-antibody reaction is one of the most critical detection techniques in the fields of medicine, biology, environmental science, and food safety. Traditional and classical methods for detecting antigen and antibody encounter many problems, such as time-consuming, high cost, and low accuracy. A novel immune microsphere imaging technique by the microlens is used to test the changes of refractive index before and after antigen-antibody reaction. It can quickly perform qualitative and quantitative determination for antigen-antibody reaction without any labeling, premodification, postwashing, and expensive enzymes. Here, we feature and discuss its principle and advantages, structure of a microlens immunoassay instrument, and potential in measuring clinical samples. It is promising to be developed for application to diagnosis of clinical diseases.

Indexed as

Antigen-Antibody ReactionsAntibodiesAntigensDiagnostic ImagingHumansImmunoassayMicrospheresRefractometryAntibodiesAntigens

Identifiers

PMID31143781
PMCPMC6501428

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.