Trial reportBioMed research international2019
Photobiomodulation by a 635nm Diode Laser on Peri-Implant Bone: Primary and Secondary Stability and Bone Density Analysis-A Randomized Clinical Trial.
Trial report in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06444334 (Evaluation of the Effect of Laser Biostimulation on Implant Covered With PRF in Controlled Diabetic Patients), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Effect of Laser Biostimulation on Implant Covered With PRF in Controlled Diabetic Patients: A Randomized Clinical Trial
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- The effect of Photobiomodulation therapy on implant stability in patients receiving dental implants- a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Comprehensive Effects of Photobiomodulation Therapy as an Adjunct to Post-orthodontic Treatment Care: A Systematic Review.Oral health & preventive dentistry · 2021Pooled it
- Correlation between insertion torque value and bone density in D3 and D4 bone following photobiomodulation: a randomised interventional study.BMC oral health · 2026Trial
- Effectiveness of the dual wavelength diode laser as an adjunct to non-surgical treatment in treating periodontal pocket in periodontitis patients: A randomized clinical study.Lasers in medical science · 2025Trial
- Enhanced Recovery of Local Anesthesia in Pediatric Patients: The Impact of Photobiomodulation on Reversing Anesthesia Effects.Medical science monitor : international medical journal of experimental and clinical research · 2024Trial
- Photobiomodulation in dental implant stability and post-surgical healing and inflammation. A randomised double-blind study.Clinical oral implants research · 2023Trial
- Influence of low-level laser therapy on implant stability in implants placed in healed sites: a randomized controlled trial.International journal of implant dentistry · 2021Trial
- Effect of ozone and diode laser (635 nm) in reducing orthodontic pain in the maxillary arch-a randomized clinical controlled trial.Lasers in medical science · 2020Trial
- Photobiomodulation in Dental Implant Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Dentistry journal · 2026Review
- Effects of Intraoperative Ozone Application on Early Implant Stability: A Randomized Split-Mouth Clinical Trial.Journal of functional biomaterials · 2026Article
- From Disease Control to Long-Term Stability: Regenerative and Prosthetic Management of Peri-Implantitis-A Five-Year Case Report.Reports (MDPI) · 2026Article
- Cross-Linked Hyaluronic Acid and Laser Photobiomodulation in Guided Bone Regeneration (GBR): A Case Report Describing a New Combined Technique.Case reports in dentistry · 2026Article
- Multiwave Locked System Laser Treatment Reduces the Bacterial Load in the Gingival Sulcus of Dogs After Plaque Removal.Veterinary sciences · 2025Article
- Efficacy of Light-Emitting Diode-Mediated Photobiomodulation in Tendon Healing in a Murine Model.International journal of molecular sciences · 2025Article
- Comparative analysis of osteointegration in photostimulated dental implants: 650-976 nm diode lasers versus growth factors.Journal of medicine and life · 2024Article
- Effect of Photobiomodulation on Crestal Bone Density Around Dental Implants: A Case Report.Cureus · 2024Article
- The effect of bone remodeling with photobiomodulation in dentistry: a review study.Lasers in medical science · 2023Review
- Photobiomodulation stimulates surrounding bone formation and increases stability of titanium alloy miniscrews in ovariectomized rats.Lasers in medical science · 2022Article
- The Effect of Photobiomodulation Therapy on the Stability of Orthodontic Mini-implants in Human and Animal Studies: A Systematic Review and Meta-analysis.Journal of lasers in medical sciences · 2022Review
- The use of photobiomodulation therapy or LED and mineral trioxide aggregate improves the repair of complete tibial fractures treated with wire osteosynthesis in rodents.Lasers in medical science · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionVarious procedures in dental implantology are performed to enhance the bone healing process and implant stability. One of these methods can be a low-level laser therapy (LLLT).
objectivesThe aim of our study was to evaluate the stabilization (primary and secondary) and bone density in peri-implant zone after LLLT protocol using a 635 nm diode laser. MATERIAL AND
methodsThe research included 40 implants placed in the posterior region of a mandible in 24 patients (8 women and 16 man; age: 46.7 ± 8.7 years). The patients were randomly divided into 2 groups G1 (n=12, 18 implants) and G2 (n=12, 22 implants) according to the treatment procedure; G1 (test): 635 nm laser, with handpiece diameter: 8mm, output power: 100mW, spot area: 0.5024cm
resultsThe average implant stability at different time points showed lower PTV value (higher stability) at 2
conclusionThe application of the 635 nm diode laser enhanced secondary implant stability and bone density. However, to assess the impact of the LLLT on peri-implant bone with different bone densities, further well-controlled long-term trials on larger study groups are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.