ArticleFrontiers in bioengineering and biotechnology2019
Cytocompatible and Anti-bacterial Adhesion Nanotextured Titanium Oxide Layer on Titanium Surfaces for Dental and Orthopedic Implants.
Article in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Functionalization Strategies of Non-Isocyanate Polyurethanes (NIPUs): A Systematic Review of Mechanical and Biological Advances.Polymers · 2025Review
- Metasurface-assisted bioelectronics: bridging photonic innovation with biomedical implants.Light, science & applications · 2025Article
- Critical Questions Surrounding the Shot-Blasting Treatment of Titanium Dental Implants.Materials (Basel, Switzerland) · 2025Review
- Recent Advances and Prospects in β-type Titanium Alloys for Dental Implants Applications.ACS biomaterials science & engineering · 2024Review
- Anticorrosion and Antimicrobial Tannic Acid-Functionalized Ti-Metallic Glass Ribbons for Dental Abutment.ACS applied bio materials · 2024Article
- Article
- Evaluation of the immune response of peripheral blood mononuclear cells cultured on Ti6Al4V-ELI polished or etched surfaces.Frontiers in bioengineering and biotechnology · 2024Article
- Enhanced osseointegration of drug eluting nanotubular dental implants: AnBioactive materials · 2023Article
- Key topographic parameters driving surface adhesion of Porphyromonas gingivalis.Scientific reports · 2023Article
- Development, Analytical Characterization, and Bioactivity Evaluation ofMolecules (Basel, Switzerland) · 2023Article
- Effect ofMaterials (Basel, Switzerland) · 2023Article
- Deposition of Antioxidant and Cytocompatible Caffeic Acid-Based Thin Films onto Ti6Al4V Alloys through Hexamethylenediamine-Mediated Crosslinking.ACS applied materials & interfaces · 2023Article
- Biocomposite Coatings Doped with Magnesium and Zinc Ions in Chitosan Matrix for Antimicrobial Applications.Materials (Basel, Switzerland) · 2023Article
- The Clinical Use of Osteobiologic and Metallic Biomaterials in Orthopedic Surgery: The Present and the Future.Materials (Basel, Switzerland) · 2023Review
- Can Superhydrophobic PET Surfaces Prevent Bacterial Adhesion?Nanomaterials (Basel, Switzerland) · 2023Article
- Emerging Trends in Advanced Translational Applications of Silver Nanoparticles: A Progressing Dawn of Nanotechnology.Journal of functional biomaterials · 2023Review
- Antibacterial activity, cytocompatibility, and thermomechanical stability of TiMaterials today. Bio · 2022Article
- Influence of surface electric charge of Ti implants on osteoblastic interaction: A systematic review.The Saudi dental journal · 2022Review
- The response of soft tissue cells to Ti implants is modulated by blood-implant interactions.Materials today. Bio · 2022Article
- Current Knowledge on Biomaterials for Orthopedic Applications Modified to Reduce Bacterial Adhesive Ability.Antibiotics (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is widely recognized that surface nanotextures applied on a biomaterial can affect wettability, protein absorption and cellular and/or bacterial adhesion; accordingly, they are nowadays of great interest to promote fast osseointegration and to maintain physiological healing around biomedical implants. In order to be suitable for clinical applications, surface nanotextures must be not only safe and effective, but also, they should be produced through industrial processes scalable to real devices with sustainable processes and costs: this is often a barrier to the market entry. Based on these premises, a chemical surface treatment designed for titanium and its alloys able to produce an oxide layer with a peculiar sponge like nanotexture coupled with high density of hydroxyl group is here presented. The modified Ti-based surfaces previously showed inorganic bioactivity intended as the ability to induce apatite precipitation in simulated body fluid. Physicochemical properties and morphology of the obtained layers have been characterized by means of FESEM, XPS, and Zeta-potential. Biological response to osteoblasts progenitors and bacteria has been tested. The here proposed nanotextured surfaces successfully supported osteoblasts progenitors' adhesion, proliferation and extracellular matrix deposition thus demonstrating good biocompatibility. Moreover, the nanotexture was able to significantly reduce bacteria surface colonization when the orthopedic and the periodontal pathogens
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