ArticleJournal of family medicine and primary care2019
Relation of systolic and diastolic epicardial adipose tissue thickness with presence and severity of coronary artery disease (The EAT CAD study).
Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Systolic Versus Diastolic Echocardiographic Assessment of Epicardial Adipose Tissue for the Detection of Obstructive Coronary Artery Disease: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Non-enhanced CT-based radiomics signature of epicardial adipose tissue for screening coronary heart disease.Frontiers in cardiovascular medicine · 2026Article
- Epicardial fat thickness predicts severe coronary artery disease and high mortality risk among ST-elevation myocardial infarction patients.Echo research and practice · 2025Article
- Ethnic disparities and its association between epicardial adipose tissue thickness and cardiometabolic parameters.Adipocyte · 2024Article
- The Role of Epicardial Adipose Tissue in Acute Coronary Syndromes, Post-Infarct Remodeling and Cardiac Regeneration.International journal of molecular sciences · 2024Review
- Relationship between quantitative epicardial adipose tissue based on coronary computed tomography angiography and coronary slow flow.BMC cardiovascular disorders · 2023Article
- The Role of Epicardial Adipose Tissue in the Development of Atrial Fibrillation, Coronary Artery Disease and Chronic Heart Failure in the Context of Obesity and Type 2 Diabetes Mellitus: A Narrative Review.Journal of cardiovascular development and disease · 2022Review
- Epicardial Adipose Tissue as an Independent Cardiometabolic Risk Factor for Coronary Artery Disease.Cureus · 2022Review
- Association of epicardial adipose tissue with different stages of coronary artery disease: A cross-sectional UK Biobank cardiovascular magnetic resonance imaging substudy.International journal of cardiology. Heart & vasculature · 2022Article
- PCSK9 Expression in Epicardial Adipose Tissue: Molecular Association with Local Tissue Inflammation.Mediators of inflammation · 2020Article
- Leptin Expression in Human Epicardial Adipose Tissue Is Associated with Local Coronary Atherosclerosis.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Use of dabigatran for treatment of left ventricular thrombus: A tertiary care center experience.Journal of family medicine and primary care · 2019Article
- Study of correlation between epicardial fat thickness and severity of coronary artery disease.Indian heart journalObservational
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent studies have shown EAT to be an indicator of cardiovascular risk and atherosclerotic plaque development. However, such data is sparse from Indian sub-continent. The present study evaluated the relationship of EAT as determined by echocardiography to the presence and severity of coronary artery disease (CAD). MATERIALS AND
methodsThis was a cross-sectional observational study constituting 500 patients including 250 with angiographically normal coronary arteries (non-CAD group), and 250 patients with significant CAD on coronary angiogram (CAD group). CAD severity was assessed by Gensini and SYNTAX scores.
resultsThe mean systolic and diastolic EAT thickness in the CAD group (5.7 ± 1.5 mm and 4.3 ± 1.1 mm) were significantly higher than the non-CAD group (4.2 ± 1.2 mm and 3.2 ± 1.2 mm), both
conclusionSystolic and diastolic EAT thicknesses are increased in CAD patients and related to both presence and severity of CAD. EAT, being modifiable, may be an attractive target for future interventions to reduce CV risk and has potential to monitor the response to life-style modification and therapy. However, larger and prospective studies required to validate these findings.
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