Evidence map›Paper›PMID 31143741›Full record

ArticleJournal of family medicine and primary care2019

Relation of systolic and diastolic epicardial adipose tissue thickness with presence and severity of coronary artery disease (The EAT CAD study).

Bhupendra Verma, Deepak Katyal, Akhilesh Patel, Vivek Raj Singh, Senthil Kumar

Abstract read
In one paragraph

Article in Journal of family medicine and primary care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Review
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  10. Article
  11. Leptin Expression in Human Epicardial Adipose Tissue Is Associated with Local Coronary Atherosclerosis.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  12. Article
  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bhupendra VermaDepartment of Cardiology, Ujala Hospital, Kashipur, Uttarakhand, India.
Deepak KatyalDepartment of Cardiology, Columbia Asia Hospital, Patiala, Punjab, India.
Akhilesh PatelAbhigya Heart Care Centre, Gorakhpur, Uttar Pradesh, India.
Vivek Raj SinghVardhan Heart Clinic, Varanasi, Uttar Pradesh, India.
Senthil KumarPerambalur Railway Hospital, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have shown EAT to be an indicator of cardiovascular risk and atherosclerotic plaque development. However, such data is sparse from Indian sub-continent. The present study evaluated the relationship of EAT as determined by echocardiography to the presence and severity of coronary artery disease (CAD). MATERIALS AND

methodsThis was a cross-sectional observational study constituting 500 patients including 250 with angiographically normal coronary arteries (non-CAD group), and 250 patients with significant CAD on coronary angiogram (CAD group). CAD severity was assessed by Gensini and SYNTAX scores.

resultsThe mean systolic and diastolic EAT thickness in the CAD group (5.7 ± 1.5 mm and 4.3 ± 1.1 mm) were significantly higher than the non-CAD group (4.2 ± 1.2 mm and 3.2 ± 1.2 mm), both

conclusionSystolic and diastolic EAT thicknesses are increased in CAD patients and related to both presence and severity of CAD. EAT, being modifiable, may be an attractive target for future interventions to reduce CV risk and has potential to monitor the response to life-style modification and therapy. However, larger and prospective studies required to validate these findings.

Indexed as

Coronary artery diseaseechocardiographyepicardial fatGensini scoresyntax score

Identifiers

PMID31143741
PMCPMC6510107

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