Evidence map›Paper›PMID 31143705›Full record

ArticleFrontiers in oncology2019

Downregulation of Fat Mass and Obesity Associated (FTO) Promotes the Progression of Intrahepatic Cholangiocarcinoma.

Zhuo-Xian Rong, Zhi Li, Jun-Ju He, Li-Yu Liu, Xin-Xin Ren, Jie Gao, Yun Mu, Yi-Di Guan, Yu-Mei Duan, Xiu-Ping Zhang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 142 citations in OpenAlex.

  1. DecreasedBioMed research international · 2020
    Trial
  2. Review
  3. Article
  4. FTO-mediated mTranslational cancer research · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Landscape of mFrontiers in pharmacology · 2024
    Review
  16. Review
  17. Review
  18. METTL5-mediated 18S rRNA mMolecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  19. Article
  20. Expression of mCartilage · 2023
    Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Zhuo-Xian RongCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Zhi LiCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Jun-Ju HeCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Li-Yu LiuCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Xin-Xin RenCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Jie GaoCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Yun MuCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Yi-Di GuanCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Yu-Mei DuanDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Xiu-Ping ZhangDepartment of Hepatic Surgery VI (Ward I), Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, China.
De-Xiang ZhangGeneral Surgery Department, Zhongshan-Xuhui Hospital Affiliated to Fudan University, Shanghai, China.
Nan LiDepartment of Hepatic Surgery VI (Ward I), Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, China.
Yue-Zhen DengCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Lun-Quan SunCenter for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, China.
Xiangya Hospital Central South University · CNCentral South University · CNSecond Military Medical University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrahepatic cholangiocarcinoma (ICC) ranks as the second most malignant type of primary liver cancer with a high degree of incidence and a very poor prognosis. Fat mass and obesity-associated protein (FTO) functions as an eraser of the RNA m

Indexed as

FTOICCmetastasisRNA m6A modificationTEAD2

Identifiers

PMID31143705
PMCPMC6521779
OpenAlexW2944063284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.