Evidence map›Paper›PMID 31143655›Full record

ArticleQuantitative imaging in medicine and surgery2019

The value of the computer-aided diagnosis system for thyroid lesions based on computed tomography images.

Chenbin Liu, Shanshan Chen, Yunze Yang, Dangdang Shao, Wenxian Peng, Yan Wang, Yihong Chen, Yuenan Wang

Open access · diamondAbstract read
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Article in Quantitative imaging in medicine and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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  5. Computer-aided detection of prostate cancer in early stages using multi-parameter MRI: A promising approach for early diagnosis.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Chenbin LiuCollege of Medical Imaging, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Shanshan ChenCollege of Medical Imaging, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Yunze YangBiodesign Institute, Arizona State University, Tempe, AZ, USA.
Dangdang ShaoBiodesign Institute, Arizona State University, Tempe, AZ, USA.
Wenxian PengCollege of Medical Imaging, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China.
Yan WangBiodesign Institute, Arizona State University, Tempe, AZ, USA.
Yihong ChenDepartment of Radiology, Hangzhou Medical College, Hangzhou 310053, China.
Yuenan WangRadiation Oncology, Chinese Academy of Medical Science (CAMS) Shenzhen Cancer Hospital, Shenzhen 518117, China.
Arizona State University · USShanghai University of Medicine and Health Sciences · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNHangzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid nodules are commonly found at palpation amounting to 4-7% of the asymptomatic population and 50% of the cases are found at autopsy. Only a small proportion of thyroid nodules are malignant. The major challenge is the differential diagnosis of benign or malignant thyroid nodules, so we aim to develop the computer-assisted diagnostic method based on computed tomography (CT) images for thyroid lesions.

methodsIn this study, we retrospectively collected 52 benign and 46 malignant thyroid nodules from 90 patients in CT examinations, together with the pathologist findings and radiology diagnosis. The first-order statistic and gray-level co-occurrence matrix features were extracted from thyroid computed tomography images. These texture features were used to assess the malignancy risk of the thyroid nodules. Several classification algorithms, including support vector machine, linear discriminant analysis, random forest, and bootstrap aggregating, were applied in the prediction. Leave-one-out cross-validation was used to evaluate the performance of thyroid cancer recognition.

resultsIn thyroid cancer identification based on a computed tomography image, we found the system using 17 texture features and support vector machine performed well. The accuracy, area under the receiver operating characteristic curve, sensitivity, specificity, positive predictive value, and negative predictive value, were 0.8673, 0.9105, 0.9130, 0.8269, 0.8235 and 0.9146, respectively.

conclusionsThe proposed computer-aided diagnosis system provides a good assessment of the malignancy-risk of the thyroid nodules, which may help radiologists to improve the accuracy and efficiency of thyroid diagnosis.

Indexed as

Computed tomography (CT)computer-aided diagnosistexture analysisthyroid cancer

Identifiers

PMID31143655
PMCPMC6511723
OpenAlexW2940024114

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.