Evidence map›Paper›PMID 31143527›Full record

ArticleTranslational vision science & technology2019

Corneal Stability of LASIK and SMILE When Combined With Collagen Cross-Linking.

Aris Konstantopoulos, Yu-Chi Liu, Ericia P Teo, Chan L Nyein, Gary H Yam, Jodhbir S Mehta

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Aris KonstantopoulosSingapore Eye Research Institute, Singapore.
Yu-Chi LiuSingapore Eye Research Institute, Singapore.
Ericia P TeoSingapore Eye Research Institute, Singapore.
Chan L NyeinSingapore Eye Research Institute, Singapore.
Gary H YamSingapore Eye Research Institute, Singapore.
Jodhbir S MehtaSingapore Eye Research Institute, Singapore.
Singapore Eye Research Institute · SGNanyang Technological University · SGUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigate whether small incision lenticule extraction (SMILE) is associated with less ectasia than laser-assisted in-situ keratomileusis (LASIK) and whether concomitant collagen cross-linking (CXL) is protective in SMILE Xtra and LASIK Xtra.

methodsUsing an established LASIK rabbit ectasia model, we performed -5 diopter (D) LASIK on six eyes and -5 D SMILE on six eyes; five eyes had -5 D LASIK Xtra, five eyes -5 D SMILE Xtra. Anterior segment optical coherence tomography and corneal topography were performed preoperatively and 2, 4, and 6 weeks postoperatively. Mean (standard deviation [SD]) values of postoperative keratometry (K), maximum posterior elevation (MPE) and minimum corneal thickness (CT) were compared to preoperatively and among the surgical groups (paired

resultsMean (SD) K values decreased significantly following SMILE, SMILE Xtra, LASIK, and LASIK Xtra. The MPE increased significantly (

conclusionsSMILE may have less potential than LASIK to induce ectasia. LASIK Xtra and SMILE Xtra showed the smallest increase in MPE. TRANSLATIONAL RELEVANCE: Concomitant CXL may be protective following keratorefractive surgery and may reduce further the risk of ectasia.

Indexed as

collagen cross-linkingectasiaLASIKLASIK XtraSMILE

Identifiers

PMID31143527
PMCPMC6526961
OpenAlexW2945772091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.