ArticleBiomedical optics express2019
Ergonomic handheld OCT angiography probe optimized for pediatric and supine imaging.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care (BabySTEPS)
Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care 2 and School Age Follow on Study (BabySTEPS2)
Who cites it
56 citing papers in PubMed, 85 citations in OpenAlex.
- Effect of Prematurity on Foveal Development During Infancy: Increased Foveal Inner and Outer Retina Layer Thicknesses in Extremely Premature Infants.Investigative ophthalmology & visual science · 2026Observational
- Barriers to accessible ophthalmic imaging device uptake: an exploratory study of ophthalmology care provider perspectives.Eye (London, England) · 2026Article
- Intensity Variance-Guided Automated Robotic Optical Coherence Tomography System for Ophthalmic Applications.Journal of biophotonics · 2026Article
- Management of incontinentia pigmenti retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
- Normative Optical Coherence Tomography Angiography Metrics of Macular Vessel Density and Foveal Avascular Zone in Healthy Children.Journal of clinical medicine · 2025Article
- Handheld 400kHz optical coherence tomography angiography visualizes microvascular details in infants with advanced retinopathy of prematurity.American journal of ophthalmology case reports · 2025Article
- Non-mydriatic handheld optical coherence tomography for panretinal imaging.Biomedical optics express · 2025Article
- Mobile Robotic Optical Coherence Tomography System for Ophthalmic Imaging in Clinical Environments.... International Symposium on Medical Robotics. International Symposium on Medical Robotics · 2025Article
- Recent Optical Coherence Tomography (OCT) Innovations for Increased Accessibility and Remote Surveillance.Bioengineering (Basel, Switzerland) · 2025Review
- Sensor-driven digital motion correction of robotically-aligned optical coherence tomography retinal volumes.Biomedical optics express · 2025Article
- Advances in OCT Angiography.Translational vision science & technology · 2025Review
- New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025Review
- Investigation of the Reproducibility of Portable Optical Coherence Tomography in Diabetic Macular Edema.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Optimization of handheld spectrally encoded coherence tomography and reflectometry for point-of-care ophthalmic diagnostic imaging.Journal of biomedical optics · 2024Article
- Vascular imaging findings in retinopathy of prematurity.Acta ophthalmologica · 2024Review
- Repeatability and reproducibility of quantitative OCT angiography measurements from table-top and portable Flex Spectralis devices.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Panretinal handheld OCT angiography for pediatric retinal imaging.Biomedical optics express · 2024Article
- Handheld contact-type OCT and color fundus system for retinal imaging.Biomedical optics express · 2024Article
- Five degrees-of-freedom mechanical arm with remote center of motion (RCM) device for volumetric optical coherence tomography (OCT) retinal imaging.Biomedical optics express · 2024Article
- A pilot optical coherence tomography angiography classification of retinal neovascularization in retinopathy of prematurity.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
OCT angiography is a functional extension of OCT that allows for non-invasive imaging of retinal microvasculature. However, most current OCT angiography systems are tabletop systems that are typically used for imaging compliant, seated subjects. These systems cannot be readily applied for imaging important patient populations such as bedridden patients, patients undergoing surgery in the operating room, young children in the clinic, and infants in the intensive care nursery. In this manuscript, we describe the design and development of a non-contact, handheld probe optimized for OCT angiography that features a novel diverging light on the scanner optical design that provides improved optical performance over traditional OCT scanner designs. Unlike most handheld OCT probes, which are designed to be held by the side of the case or by a handle, the new probe was optimized for ergonomics of supine imaging where imagers prefer to hold the probe by the lens tube. The probe's design also includes an adjustable brace that gives the operator a point of contact closer to the center of mass of the probe, reducing the moment of inertia around the operator's fingers, facilitating stabilization, and reducing operator fatigue. The probe supports high-speed imaging using a 200 kHz swept source OCT engine, has a motorized stage that provides + 10 to -10 D refractive error correction and weighs 700g. We present initial handheld OCT angiography images from healthy adult volunteers, young children during exams under anesthesia, and non-sedated infants in the intensive care nursery. To the best of our knowledge, this represents the first reported use of handheld OCT angiography in non-sedated infants, and the first handheld OCT angiography images which show the clear delineation of key features of the retinal capillary complex including the foveal avascular zone, peripapillary vasculature, the superficial vascular complex, and the deep vascular complex.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.