ArticleBiomedical optics express2019
Brillouin micro-spectroscopy of subchondral, trabecular bone and articular cartilage of the human femoral head.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Natural Biomaterials for Osteochondral Repair: From Source to Strategy.Advanced healthcare materials · 2026Review
- Bone formation niche dysfunction in osteoporosis: insights from single-cell and spatial transcriptomic studies.Frontiers in endocrinology · 2026Review
- Brillouin microscopy.Nature reviews. Methods primers · 2024Article
- Brillouin-Raman micro-spectroscopy and machine learning techniques to classify osteoarthritic lesions in the human articular cartilage.Scientific reports · 2023Article
- Microscale mechanochemical characterization of drying oil films by in situ correlative Brillouin and Raman spectroscopy.Science advances · 2022Article
- Article
- Non-contact elastography methods in mechanobiology: a point of view.European biophysics journal : EBJ · 2022Review
- Brillouin-Raman microspectroscopy for the morpho-mechanical imaging of human lamellar bone.Journal of the Royal Society, Interface · 2022Article
- Piezoelectric and Opto-Acoustic Material Properties of Bone.Advances in experimental medicine and biology · 2022Article
- Brillouin and Raman Micro-Spectroscopy: A Tool for Micro-Mechanical and Structural Characterization of Cortical and Trabecular Bone Tissues.Materials (Basel, Switzerland) · 2021Article
- Brillouin Spectroscopy: From Biomedical Research to New Generation Pathology Diagnosis.International journal of molecular sciences · 2021Review
- Mapping mechanical properties of biological materials via an add-on Brillouin module to confocal microscopes.Nature protocols · 2021Article
- Mechano-chemistry of human femoral diaphysis revealed by correlative Brillouin-Raman microspectroscopy.Scientific reports · 2020Article
- Viscoelastic properties of biopolymer hydrogels determined by Brillouin spectroscopy: A probe of tissue micromechanics.Science advances · 2020Article
- Brillouin Light Scattering Microspectroscopy for Biomedical Research and Applications: introduction to feature issue.Biomedical optics express · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brillouin micro-spectroscopy is applied for investigating the mechanical properties of bone and cartilage tissues of a human femoral head. Distinctive mechanical properties of the cartilage surface, subchondral and trabecular bone are reported, with marked heterogeneities at both micrometric and millimetric length scales. A ubiquitous soft component is reported for the first time, characterized by a longitudinal modulus of about 4.3 GPa, possibly related to the amorphous phase of the bone. This phase is mixed, at micrometric scales, with a harder component, ascribed to mineralized collagen fibrils, characterized by a longitudinal modulus ranging between 16 and 25 GPa.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.