Evidence map›Paper›PMID 31143502›Full record

ArticleBiomedical optics express2019

Characterizing intestinal strictures of Crohn's disease

Hao Lei, Laura A Johnson, Kathryn A Eaton, Shengchun Liu, Jun Ni, Xueding Wang, Peter D R Higgins, Guan Xu

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Guided Multispectral Optoacoustic Tomography for 3D Imaging of the Murine Colon.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hao LeiDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Laura A JohnsonDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Kathryn A EatonDepartment of Microbiology and Immunology, University of Michigan Medical Center, Ann Arbor, Michigan, MI 48109, USA.
Shengchun LiuCollege of Physical Science and Technology, Heilongjiang University, Harbin, 150080, China.
Jun NiDepartment of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Xueding WangDepartment of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Peter D R HigginsDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Guan XuDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

Funding

Physiology of Inflammatory Arthritis in High ResolutionR01AR060350 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, XUEDING · 2011 to 2021
$6.0M
Real time fine needle assessment of architectural heterogeneity in prostate cancerR37CA222829 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, GUAN · 2019 to 2025
$3.2M
In vivo photoacoustic biopsy for intestinal strictures in Crohn's diseaseR21AI122098 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HIGGINS, PETER D.R., XU, GUAN · 2016 to 2017
$397k
NCI NIH HHS R37 CA222829NIAID NIH HHS R21 AI122098NIAMS NIH HHS R01 AR060350
6 · The paper itself

Abstract

Crohn's disease (CD) is one type of inflammatory bowel disease where both inflammation and fibrosis cause the thickening of the bowel wall and development of the strictures. Accurate assessment of the strictures is critical for the management of CD because the fibrotic strictures must be removed surgically. In this study, a prototype capsule-shaped acoustic resolution photoacoustic (PA) endoscope, which can perform mulitwavelength side-view scanning, was developed to characterize the intestinal strictures of CD. The imaging performance of the probe was tested in phantom experiments and a rabbit trinitrobenzene sulfonic acid (TNBS) model with acute (inflammatory only) or chronic (mixed fibrotic and inflammatory) colitis

Identifiers

PMID31143502
PMCPMC6524586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.