Evidence map›Paper›PMID 31143494›Full record

ArticleBiomedical optics express2019

Development of a clinical prototype of a miniature hand-held optical coherence tomography probe for prematurity and pediatric ophthalmic imaging.

Shaozhen Song, Kanheng Zhou, Jing Jiang Xu, Qinqin Zhang, Shuyuan Lyu, Ruikang Wang

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 58 citations in OpenAlex.

  1. Towards maximizing optical access through Smart Dura.Journal of neural engineering · 2026
    Article
  2. Assessing visual and refractive outcomes of subretinal fluid detected by handheld swept-source optical coherence tomography in full-term newborns.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Advances in OCT Angiography.Translational vision science & technology · 2025
    Review
  8. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Panretinal Optical Coherence Tomography.IEEE transactions on medical imaging · 2023
    Article
  17. Article
  18. Observational
  19. Review
  20. Insights into the developing fovea revealed by imaging.Progress in retinal and eye research · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Shaozhen SongDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.
Kanheng ZhouDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.
Jing Jiang XuDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.
Qinqin ZhangDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.
Shuyuan LyuDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.
Ruikang WangDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.
University of Washington · USUniversity of Dundee · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a novel design and operation of a highly integrated miniature handheld OCT probe, with high-speed angiography function that can be used in clinical settings for young children and infants, providing rapid, non-invasive structural and angiographic imaging of the retina and choroid. The imaging system is operated at 200 kHz, with 3D OCT and OCTA scan time of 0.8 and 3.2 seconds, respectively, and the scanning angle on the pupil is ± 36°, covering the full perifoveal region. Operator assisting features of the direct-view iris camera and on-probe display are integrated into the hand-held probe, and the fixation target can display animations to attract the attention of young subjects. Compared to conventional OCT systems, the high-speed hand-held OCT system significantly improves the operator's experience and scanning efficiency, which is important for imaging infants. Imaging results indicate a significant reduction in total time consumption in pediatric ophthalmic imaging sessions, as well as the image quality of OCT angiography.

Identifiers

PMID31143494
PMCPMC6524597
OpenAlexW2935768853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.