Evidence map›Paper›PMID 31143245›Full record

ArticleGut pathogens2019

Variation of human norovirus GII genotypes detected in Ibaraki, Japan, during 2012-2018.

Takumi Motoya, Masahiro Umezawa, Aoi Saito, Keiko Goto, Ikuko Doi, Setsuko Fukaya, Noriko Nagata, Yoshiaki Ikeda, Kaori Okayama, Jumpei Aso and 6 more

Open access · goldAbstract read
In one paragraph

Article in Gut pathogens, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Takumi MotoyaIbaraki Prefectural Institute of Public Health, Ibaraki, Japan.
Masahiro UmezawaIbaraki Prefectural Institute of Public Health, Ibaraki, Japan.
Aoi SaitoIbaraki Prefectural Institute of Public Health, Ibaraki, Japan.
Keiko GotoIbaraki Prefectural Institute of Public Health, Ibaraki, Japan.
Ikuko DoiIbaraki Prefectural Institute of Public Health, Ibaraki, Japan.
Setsuko FukayaIbaraki Prefectural Institute of Public Health, Ibaraki, Japan.
Noriko NagataIbaraki Prefectural Institute of Public Health, Ibaraki, Japan.
Yoshiaki IkedaIbaraki Prefectural Institute of Public Health, Ibaraki, Japan.
Kaori OkayamaGunma Paz University Graduate School of Health Science, Gunma, 370-0006 Japan.
Jumpei AsoGunma Paz University Graduate School of Health Science, Gunma, 370-0006 Japan.
Yuki MatsushimaKawasaki City Institute for Public Health, Kawasaki, Kanagawa Japan.
Taisei IshiokaTakasaki City Public Health Center, Gunma, Japan.
Akihide Ryo7Department of Molecular Biodefence Research, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.
Nobuya Sasaki2Faculty of Veterinary Medicine, Kitasato University, Aomori, Japan.
Kazuhiko Katayama8Laboratory of Viral Infection I, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan.
Hirokazu KimuraGunma Paz University Graduate School of Health Science, Gunma, 370-0006 Japan.
Ibaraki Prefectural Police · JPGumma Paz College · JPKitasato University · JPYokohama City University · JPTakasaki City University of Economics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman norovirus (HuNoV) is the major cause of viral acute gastroenteritis for all age groups in various countries. HuNoV GII in particular accounted for the majority of norovirus outbreaks, among which GII.4 caused repeated outbreaks for a long time. Besides GII.4, other norovirus genotypes, GII.2, GII.6, and GII.17, have also been prevalent in various contexts in recent years, but few detailed epidemiological studies of them have been performed and are poorly understood. We thus conducted an epidemiological analysis of HuNoV GII in Ibaraki Prefecture, Japan, by performing surveillance in the six seasons from September 2012 to August 2018.

resultsHuNoV GI occurred almost sporadically for all genotypes; however, each genotype of GII exhibited its typical epidemiological characteristics. Although the number of outbreaks of GII.4 decreased season by season, it reemerged in 2017/2018 season. The timing of the epidemic peak in terms of number of cases for GII.17 differed from that for the other genotypes. The patients age with GII.2 and GII.6 were younger and outbreak of GII.17 occurred frequently as food poisoning. Namely, the primarily infected outbreak group differed for each genotype of HuNoV GII. Moreover, the viral load of patients differed according to the genotype.

conclusionsVarious HuNoV genotypes including GII.2, GII.4, GII.6, and GII.17 were shown to be associated with various types of outbreak sites (at childcare and educational facilities, involving cases of food poisoning, and at elderly nursing homes) in this study. These genotypes emerged in recent years, and their prevalence patterns differed from each other. Moreover, differences in outbreak sites and viral load of patients among the genotypes were identified.

Indexed as

EpidemiologyGenotypeNorovirusOutbreakViral load

Identifiers

PMID31143245
PMCPMC6533662
OpenAlexW2947682352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.