Evidence map›Paper›PMID 31143190›Full record

ArticleFrontiers in immunology2019

α7 Nicotinic Acetylcholine Receptor Signaling Modulates Ovine Fetal Brain Astrocytes Transcriptome in Response to Endotoxin.

Mingju Cao, James W MacDonald, Hai L Liu, Molly Weaver, Marina Cortes, Lucien D Durosier, Patrick Burns, Gilles Fecteau, André Desrochers, Jay Schulkin and 5 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Inflammaging and Brain Aging.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Mingju CaoDepartment of Obstetrics and Gynaecology and Department of Neurosciences, CHU Ste-Justine Research Centre, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
James W MacDonaldDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, United States.
Hai L LiuDepartment of Obstetrics and Gynaecology and Department of Neurosciences, CHU Ste-Justine Research Centre, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
Molly WeaverUW Medicine Center for Precision Diagnostics, University of Washington, Seattle, WA, United States.
Marina CortesAnimal Reproduction Research Centre (CRRA), Faculty of Veterinary Medicine, Université de Montréal, Montréal, QC, Canada.
Lucien D DurosierDepartment of Obstetrics and Gynaecology and Department of Neurosciences, CHU Ste-Justine Research Centre, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
Patrick BurnsDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Université de Montréal, Montréal, QC, Canada.
Gilles FecteauDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Université de Montréal, Montréal, QC, Canada.
André DesrochersDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Université de Montréal, Montréal, QC, Canada.
Jay SchulkinDepartment of Obstetrics and Gynecology, University of Washington, Seattle, WA, United States.
Marta C AntonelliInstituto de Biología Celular y Neurociencia "Prof. Eduardo De Robertis", Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Raphael A BernierDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
Michael DorschnerUW Medicine Center for Precision Diagnostics, University of Washington, Seattle, WA, United States.
Theo K BammlerDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, United States.
Martin G FraschDepartment of Obstetrics and Gynaecology and Department of Neurosciences, CHU Ste-Justine Research Centre, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
University of Washington · USUniversité de Montréal · CACentre Hospitalier Universitaire Sainte-Justine · CAPrecision for Medicine (United States) · USUniversity of Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation

Indexed as

alpha7 Nicotinic Acetylcholine ReceptorAnimalsAstrocytesBrainCattleCells, CulturedFetusGene Expression ProfilingLipopolysaccharidesMicrogliaNeurogenic InflammationNeuroprotectionSignal TransductionSTAT3 Transcription Factoralpha7 Nicotinic Acetylcholine ReceptorLipopolysaccharidesSTAT3 Transcription FactorastrocyteCHRNA7fetal programminginfectionLPSmicroglianeuroinflammationRNAseq

Identifiers

PMID31143190
PMCPMC6520997
OpenAlexW2946768611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.