Evidence map›Paper›PMID 31143183›Full record

ArticleFrontiers in immunology2019

Proteomic Profiling Unravels a Key Role of Specific Macrophage Subtypes in Sporadic Inclusion Body Myositis.

Andreas Roos, Corinna Preusse, Denisa Hathazi, Hans-Hilmar Goebel, Werner Stenzel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Inclusion Body Myositis and Neoplasia: A Narrative Review.International journal of molecular sciences · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. The role of interferons type I, II and III in myositis: A review.Brain pathology (Zurich, Switzerland) · 2021
    Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Andreas RoosDepartment of Neuropediatrics, Developmental Neurology and Social Pediatrics, Centre for Neuromuscular Disorders in Children, University Children's Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Corinna PreusseDepartment of Neuropathology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Denisa HathaziLeibniz-Institut für Analytische Wissenschaften -ISAS- e.V., Dortmund, Germany.
Hans-Hilmar GoebelDepartment of Neuropathology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Werner StenzelDepartment of Neuropathology, Charité -Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Humboldt-Universität zu Berlin · DECharité - Universitätsmedizin Berlin · DELeibniz Institute for Analytical Sciences - ISAS · DEUniversity of Duisburg-Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unbiased proteomic profiling was performed toward the identification of biological parameters relevant in sIBM, thus giving hints about the pathophysiological processes and the existence of new reliable markers. For that purpose, skeletal muscle biopsies from 13 sIBM and 7 non-diseased control patients were analyzed with various methods, including liquid chromatography coupled to tandem mass spectrometry (four patients). Subsequent data analysis identified key molecules further studied in a larger cohort by

Indexed as

AgedAntigens, CDAntigens, Differentiation, B-LymphocyteAntigens, Differentiation, MyelomonocyticBiopsyCD163 AntigenCohort StudiesFemaleHistocompatibility Antigens Class IIHumansMacrophage ActivationMacrophagesMaleMiddle AgedMuscle, SkeletalMyositis, Inclusion BodyAntigens, CDAntigens, Differentiation, B-LymphocyteAntigens, Differentiation, MyelomonocyticCD163 AntigenHistocompatibility Antigens Class IIinvariant chainProteomeReceptors, Cell SurfaceSTAT1 Transcription FactorCD163CD74muscle proteomicsSIGLEC1STAT1STAT6type I interferon (IFN)

Identifiers

PMID31143183
PMCPMC6522546
OpenAlexW2944141731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.