Evidence map›Paper›PMID 31143178›Full record

ArticleFrontiers in immunology2019

Organ-Specific Expression of IL-1 Receptor Results in Severe Liver Injury in Type I Interferon Receptor Deficient Mice.

Martina Anzaghe, Theresa Resch, Elea Schaser, Stefanie Kronhart, Clara Diez, Marc A Niles, Eugenia Korotkova, Stefan Schülke, Sonja Wolfheimer, Dorothea Kreuz and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Martina AnzagheSection 3/1 "Product Testing of Immunological Biomedicines", Paul-Ehrlich-Institut, Langen, Germany.
Theresa ReschSection 3/1 "Product Testing of Immunological Biomedicines", Paul-Ehrlich-Institut, Langen, Germany.
Elea SchaserSection 3/1 "Product Testing of Immunological Biomedicines", Paul-Ehrlich-Institut, Langen, Germany.
Stefanie KronhartSection 3/1 "Product Testing of Immunological Biomedicines", Paul-Ehrlich-Institut, Langen, Germany.
Clara DiezSection 3/1 "Product Testing of Immunological Biomedicines", Paul-Ehrlich-Institut, Langen, Germany.
Marc A NilesSection 3/1 "Product Testing of Immunological Biomedicines", Paul-Ehrlich-Institut, Langen, Germany.
Eugenia KorotkovaSection 3/1 "Product Testing of Immunological Biomedicines", Paul-Ehrlich-Institut, Langen, Germany.
Stefan SchülkeVice President's Research Group 1 "Molecular Allergology", Paul-Ehrlich-Institut, Langen, Germany.
Sonja WolfheimerVice President's Research Group 1 "Molecular Allergology", Paul-Ehrlich-Institut, Langen, Germany.
Dorothea KreuzSection 3/3 "Morphology", Paul-Ehrlich-Institut, Langen, Germany.
Marion WingerterDivision of Veterinary Medicine, Paul-Ehrlich-Institut, Langen, Germany.
María Matilde Bartolomé RodríguezInstitute for Internal Medicine University of Freiburg, Freiburg, Germany.
Zoe WaiblerSection 3/1 "Product Testing of Immunological Biomedicines", Paul-Ehrlich-Institut, Langen, Germany.
Paul Ehrlich Institut · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upon treatment with polyinosinic:polycytidylic acid [poly(I:C)], an artificial double-stranded RNA, type I interferon receptor-deficient (IFNAR

Indexed as

Alanine TransaminaseAnimalsCells, CulturedGene Expression RegulationHepatocytesHumansInterferon Type ILiverMiceMice, Inbred C57BLMice, KnockoutOrgan SpecificityPoly I-CReceptor, Interferon alpha-betaReceptors, Interleukin-1Alanine TransaminaseIfnar1 protein, mouseInterferon Type IPoly I-CReceptor, Interferon alpha-betaReceptors, Interleukin-1anti-inflammatorycytokinesdysregulationimmune pathologypoly(I:C)

Identifiers

PMID31143178
PMCPMC6521796
OpenAlexW2944349554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.