Evidence map›Paper›PMID 31143177›Full record

ReviewFrontiers in immunology2019

A Case for Antibodies as Mechanistic Correlates of Immunity in Tuberculosis.

Jeffrey Y Kawahara, Edward B Irvine, Galit Alter

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Monoclonal Antibodies Targeting Bacterial Infections: A Broad Review of the Field.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  5. Review
  6. A proteome-wide atlas of humoral immunity toFrontiers in immunology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Selection of vaccine-candidate peptides fromFrontiers in immunology · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. The role of antibodies in tuberculosis diagnosis, prophylaxis and therapy: a review from the ESGMYC study group.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jeffrey Y KawaharaRagon Institute of MGH, MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, United States.
Edward B IrvineRagon Institute of MGH, MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, United States.
Galit AlterRagon Institute of MGH, MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, United States.
Harvard University · USRagon Institute of MGH, MIT and Harvard · US

Funding

Bacteriology PhD Training ProgramT32AI132120 · NIAID · HARVARD MEDICAL SCHOOL · PI RUDNER, DAVID Z · 2017 to 2021
$1.7M
NIAID NIH HHS T32 AI132120
6 · The paper itself

Abstract

Tuberculosis infects one quarter of the world's population and is the leading cause of death by a single infectious agent, responsible for a reported 1.3 million deaths in 2017. While

Indexed as

AnimalsAntibodies, BacterialAntigen PresentationHumansImmunity, HumoralImmunity, InnateImmunoglobulin Fc FragmentsMycobacterium tuberculosisTuberculosisTuberculosis VaccinesAntibodies, BacterialImmunoglobulin Fc FragmentsTuberculosis Vaccinesantibodiescell-mediated immunityFc effector functionhumoral immunityinnate immune systemtuberculosis

Identifiers

PMID31143177
PMCPMC6521799
OpenAlexW2944102792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.