Evidence map›Paper›PMID 31143075›Full record

SynthesisWorld journal of gastroenterology2019

Effect of prophylactic clip placement following endoscopic mucosal resection of large colorectal lesions on delayed polypectomy bleeding: A meta-analysis.

Fares Ayoub, Donevan R Westerveld, Justin J Forde, Christopher E Forsmark, Peter V Draganov, Dennis Yang

Abstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. To clip or not to clip: still no closure for all.Translational gastroenterology and hepatology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fares AyoubDepartment of Medicine, University of Florida, Gainesville, FL 32608, United States.
Donevan R WesterveldDepartment of Medicine, University of Florida, Gainesville, FL 32608, United States.
Justin J FordeDepartment of Medicine, University of Florida, Gainesville, FL 32608, United States.
Christopher E ForsmarkDivision of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, FL 32608, United States.
Peter V DraganovDivision of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, FL 32608, United States.
Dennis YangDivision of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, FL 32608, United States. dennis.yang@medicine.ufl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe role of prophylactic clipping for the prevention of delayed polypectomy bleeding (DPB) remains unclear and conclusions from prior meta-analyses are limited due to the inclusion of variety of resection techniques and polyp sizes.

aimTo conduct a meta-analysis on the effect of clipping on DPB following endoscopic mucosal resection (EMR) of colorectal lesions ≥ 20 mm.

methodsWe performed a search of PubMed and the Cochrane library for studies comparing the effect of clipping

resultsThirteen studies with a total of 7794 polyps were identified, of which data was available on 1701 cases of EMR of lesions ≥ 20 mm. Prophylactic clipping was associated with a lower rate of DPB (1.4%) when compared to no clipping (5.2%) (pooled OR: 0.24, 95%CI: 0.12-0.50, CONLUSION: Prophylactic clipping may reduce DPB following EMR of large colorectal lesions. Future trials are needed to further identify risk factors and stratify high risk cases in order to implement a cost-effective preventive strategy.

Indexed as

Colonic PolypsColonoscopyEndoscopic Mucosal ResectionGastrointestinal HemorrhageHumansIncidencePostoperative HemorrhageTime FactorsClippingEndoscopic mucosal resectionEndoscopic resectionMeta-analysis

Identifiers

PMID31143075
PMCPMC6526150

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.