Evidence map›Paper›PMID 31143031›Full record

ArticleAnnals of pediatric cardiology

Modulation of plasma triglycerides concentration by sterol-based treatment in children carrying different genes.

Ismael San Mauro Martín, Sara Sanz Rojo, Elena Garicano Vilar, Luis Collado Yurrita, Javier Andrés Blumenfeld Olivares

Open access · diamondAbstract read
In one paragraph

Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ismael San Mauro MartínResearch Centers in Nutrition and Health, Madrid, Spain.
Sara Sanz RojoResearch Centers in Nutrition and Health, Madrid, Spain.
Elena Garicano VilarResearch Centers in Nutrition and Health, Madrid, Spain.
Luis Collado YurritaDepartment of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Javier Andrés Blumenfeld OlivaresHospital El Escorial, San Lorenzo de El Escorial, Madrid, Spain.
Hospital El Escorial · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDyslipidemias have increased during the last decades in children.

aimThe objective of this study was to analyze the influence of different polymorphisms in plasma triglyceride levels of children following a dietary treatment with plant sterols.

designA randomized, double-blind, crossover, controlled clinical trial was carried out in 26 children (16 women). MATERIALS AND

methodsCommercial milk, with 2.24 g sterols, was ingested daily during 3 weeks , and the same amount of kimmed milk without sterols, during the 3 week placebo phase. Both phases were separated by a washout period of 2 weeks. At the beginning and end of each phase, blood draws were performed.

resultsApolipoprotein A5 Ser19Trp (

conclusionsFurther studies are needed to establish which genotype combinations would be the most protective against hypertriglyceridemia.

Indexed as

Cardiovascular diseasechildrengeneticsterolstriglycerides

Identifiers

PMID31143031
PMCPMC6521671
OpenAlexW2961710195

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.