Evidence map›Paper›PMID 31143006›Full record

ArticleJournal of Indian Society of Periodontology

Comparison of effectiveness of low-dose aspirin versus omega-3 fatty acids as adjuvants to nonsurgical periodontal therapy in Type II diabetic patients with chronic periodontitis.

Prathyusha Rampally, Rekha Rani Koduganti, Sastri Nadiminty Ganapathi, Veerendranath Reddy Panthula, Prasanna Jammula Surya

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07523841 (The Efficacy of Non-surgical Periodontal Therapy in Combination With Aspirin and Omega-3 Fatty Acids.), which is not on this map. Cited by 16 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 7 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07523841 naactive not recruitingnot on this map

The Efficacy of Non-surgical Periodontal Therapy in Combination With Aspirin and Omega-3 Fatty Acids.

TypeinterventionalSponsorHanoi Medical UniversityRan2023 to 2027Enrolled120ConditionsPeriodontitis, Periodontitis (Stage 3)ArmsScaling and Root Planing (SRP), Omega-3 Fatty Acids, Low-dose aspirin
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 7 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Prathyusha RampallyDepartment of Periodontics, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, India.
Rekha Rani KodugantiDepartment of Periodontics, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, India.
Sastri Nadiminty GanapathiDepartment of Diabetology, Mohan's Diabetic Centre, Hyderabad, Telangana, India.
Veerendranath Reddy PanthulaDepartment of Periodontics, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, India.
Prasanna Jammula SuryaDepartment of Periodontics, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, India.
Kamineni Institute of Dental Sciences · INDr. Mohan's Diabetes Specialities Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextPeriodontitis and diabetes are universally prevalent diseases which are interlinked with each other. Inflammatory products released both by the microorganisms, and the host plays a pivotal role in causing both the diseases. Pentraxins are acute-phase proteins which are often found to be elevated in inflammatory states. Anti-inflammatory agents have a very important role to play in curbing infection of which, aspirin and omega-3 fatty acids (O3FAs) are being administered often nowadays. Nonsurgical periodontal therapy (NSPT) remains the gold standard of treatment, and other agents have been used as adjuvants only, to increase the efficacy of treatment.

aimsThis study compares the effects of low-dose aspirin versus O3FAs when used as adjuvants to NSPT in patients with diabetes and chronic periodontitis. SETTINGS AND

designA total of 42 patients (mean age of 30-65 years) from a diabetic center who were diagnosed with Type II diabetes and chronic periodontitis were included in the study. MATERIALS AND

methodsThis study was done in the department of periodontics of a tertiary referral care hospital in Hyderabad, in collaboration with a reputed diabetic center. STATISTICAL ANALYSIS USED: Intragroup comparison was done using the paired

resultsIntragroup comparison at baseline and 3 months after NSPT showed statistically significant results (

conclusionsO3FAs proved to be better than low-dose aspirin and placebo after NSPT.

Indexed as

Chronic periodontitisdiabetes mellituslipoxinsnonsurgical periodontal therapypentraxinresolvins

Identifiers

PMID31143006
PMCPMC6519093
OpenAlexW2942854510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.