Evidence map›Paper›PMID 31142986›Full record

ArticleJournal of conservative dentistry : JCD

Cytotoxicity evaluation of fungal-derived silver nanoparticles on human gingival fibroblast cell line: An

Kiran R Halkai, Jayashree A Mudda, Vasundhara Shivanna, Veena Patil, Vandana Rathod, Rahul Halkai

Open access · greenAbstract read
In one paragraph

Article in Journal of conservative dentistry : JCD. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Green-SynthesizedJournal of functional biomaterials · 2026
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  8. Valorization ofFrontiers in nutrition · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kiran R HalkaiDepartment of Conservative Dentistry and Endodontics, HKE's SN Institute of Dental Sciences and Research, Kalaburgi, Karnataka, India.
Jayashree A MuddaDepartment of Periodontics, HKE's SN Institute of Dental Sciences and Research, Kalaburgi, Karnataka, India.
Vasundhara ShivannaDepartment of Conservative Dentistry and Endodontics, College of Dental Sciences, Davanagere, Karnataka, India.
Veena PatilDepartment of Periodontics, HKE's SN Institute of Dental Sciences and Research, Kalaburgi, Karnataka, India.
Vandana RathodDepartment of Microbiology, Gulbarga University, Kalaburgi, Karnataka, India.
Rahul HalkaiDepartment of Conservative Dentistry and Endodontics, College of Dentistry, Gulf Medical University, Ajman, United Arab Emirates.
Bapuji Dental College and Hospital · INGulbarga University · INGulf Medical University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiosynthesized silver nanoparticles (AgNPs) have been proposed as effective antimicrobial agents against endo-perio pathogens. Determination of cytotoxicity is important for effective clinical use.

aimThe aim is to determine the cytotoxicity of fungal-derived AgNPs on human gingival fibroblast (HGF) cell line using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. MATERIALS AND

methodsHGF cell cultures were trypsinized and adjusted to 5 × 10

resultsCTC

conclusionFungal-derived AgNPs are safe to healthy cells at a concentration <260 μg/ml. Therefore, they can be effectively used for the treatment of endo-perio lesions.

Indexed as

Antimicrobial agentsbiosynthesized silver nanoparticlescytotoxicityendo–perio lesions

Identifiers

PMID31142986
PMCPMC6519193
OpenAlexW2966600101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.