ReviewJournal of anaesthesiology, clinical pharmacology2019
Multimodal analgesia as an essential part of enhanced recovery protocols in the ambulatory settings.
Review in Journal of anaesthesiology, clinical pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 75 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Double-blinded Randomized Trial Comparing Surgeon-administered Transversus Abdominis Plane (TAP) Block With Placebo After Midline Laparotomy in Gynecologic Oncology
Management of Perioperative Pain Using Erector Spinae Plane Block in Open Microscopic Lumbar Surgery
Patient-Controlled Analgesia (PCA) With Ketamine-Morphine (PCA KetaMorph) vs PCA Morphine for Postoperative Analgesia in Idiopathic Scoliosis Surgery - A Randomized Controlled Trial
Who cites it
75 citing papers in PubMed, 10 syntheses or guidelines pooled it, 144 citations in OpenAlex.
- The efficacy of ERAS-related components in orthopedic trauma surgery: a systematic review and meta-analysis of randomized controlled trials.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Pooled it
- Safety and Efficacy of Perioperative Magnesium Sulfate Injection for Postoperative Pain Management and Opioid Sparing Effects in Surgeries of the Nervous System: A Systematic Review and Meta Analysis.Current pain and headache reports · 2026Pooled it
- Intercostal Nerve Cryoablation Therapy in Thoracic and Cardiac Surgery for Postoperative Pain Management: A Systematic Review and Meta-Analysis.Interdisciplinary cardiovascular and thoracic surgery · 2026Pooled it
- Postoperative Pain Management After Lumbar Discectomy. A Systematic Review With Meta-Analyses and Trial Sequential Analyses.European journal of pain (London, England) · 2026Pooled it
- Dexmedetomidine in Mechanically Ventilated Critically Ill Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Yonsei medical journal · 2025Pooled it
- Effect of the enhanced recovery after surgery protocol in patients undergoing elective craniotomies: a systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- Effect of pain-relief nursing on activities of daily living in patients following hip arthroplasty: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Impact of enhanced recovery after surgery protocols on surgical site wound infection rates in urological procedures.International wound journal · 2024Pooled it
- Effect of single dose preoperative intravenous ibuprofen on postoperative pain and opioid consumption: a systematic review and meta-analysis.Korean journal of anesthesiology · 2021Pooled it
- Pathway for enhanced recovery after spinal surgery-a systematic review of evidence for use of individual components.BMC anesthesiology · 2021Pooled it
- Preperitoneal bupivacaine instillation in addition to TAP block for pain control in laparoscopic inguinal hernia repair: a randomised controlled trial.Hernia : the journal of hernias and abdominal wall surgery · 2025Trial
- Co-crystal of Tramadol-Celecoxib Versus Tramadol or Placebo for Acute Moderate-to-Severe Pain After Oral Surgery: Randomized, Double-Blind, Phase 3 Trial (STARDOM1).Advances in therapy · 2024Trial
- Article
- Opioid-sparing and opioid-free anaesthesia: concepts, rationale, evidence, and practical implications.Anaesthesiology intensive therapy · 2026Review
- When immunotherapy hurts: neoadjuvant PD-1 inhibitors increase opioid use after mastectomy with reconstruction.Breast cancer research and treatment · 2026Article
- Regional Anesthesia as Primary Strategy in Aesthetic Breast Augmentation Surgery: Clinical Outcomes in 627 Sedated Patients Undergoing Pectoral Nerves (PECS I-II) and Parasternal Blocks.Aesthetic plastic surgery · 2026Article
- Evaluation of relevant anatomy for cervical erector spinae plane block using paediatric computed tomography scans.Anatomy & cell biology · 2026Article
- Article
- The impact of regional block presence on large language model-based postoperative analgesia recommendations in abdominal surgery: a comparative study using real-world patient data.BMC anesthesiology · 2026Observational
- Impact of age on PUAL as an indicator of opioid effect in adult subjects.Journal of clinical monitoring and computing · 2026Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enhanced recovery after surgery protocols are multimodal perioperative care pathways designed to achieve early recovery in patients after surgical procedures by defining and maintaining preoperative organ function and minimizing the profound stress response following surgery. Enhanced recovery protocols have primarily been studied for major abdominal surgeries, however, the knowledge acquired from studying these protocols has facilitated treating patients in ambulatory settings. The key components of enhanced recovery protocols include preoperative counseling, preoperative nutrition, altering the standard perioperative fasting guidelines, and the value of carbohydrate loading up to 2 hours preoperatively, standardized analgesic, and anesthetic regimens (epidural and nonopioid analgesia) and early mobilization. A PubMed search was performed with the following key words: multimodal analgesia, enhanced recovery, ambulatory care, pain management, and opioids. We discuss the use of enhanced recovery protocols and multimodal pain care plans in the ambulatory setting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.