Evidence map›Paper›PMID 31142958›Full record

ReviewJournal of anaesthesiology, clinical pharmacology2019

Multimodal analgesia as an essential part of enhanced recovery protocols in the ambulatory settings.

Alan David Kaye, Richard D Urman, Yury Rappaport, Harish Siddaiah, Elyse M Cornett, Kumar Belani, Orlando J Salinas, Charles J Fox

3 registry-linked trialsOpen access · diamondAbstract readReview
In one paragraph

Review in Journal of anaesthesiology, clinical pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 75 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 10 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04202874 phase3unknown statusnot on this mapstarted 2020, after this paper: background citation

A Double-blinded Randomized Trial Comparing Surgeon-administered Transversus Abdominis Plane (TAP) Block With Placebo After Midline Laparotomy in Gynecologic Oncology

TypeinterventionalSponsorMcMaster UniversityRan2020 to 2021Enrolled80ConditionsGenital Neoplasm Malignant Female, Surgical Procedure, UnspecifiedArmsSurgeon-administered transversus abdominis plane (TAP)
NCT06270654 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Management of Perioperative Pain Using Erector Spinae Plane Block in Open Microscopic Lumbar Surgery

TypeinterventionalSponsorUniversity of MalayaRan2023 to 2024Enrolled40ConditionsLumbar Spine DiseaseArmsErector spinae plane block, Skin infiltration LA
NCT07452705 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Patient-Controlled Analgesia (PCA) With Ketamine-Morphine (PCA KetaMorph) vs PCA Morphine for Postoperative Analgesia in Idiopathic Scoliosis Surgery - A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of MalayaRan2026 to 2028Enrolled114ConditionsAdolescent Idiopathic Scoliosis (AIS)ArmsKetamine-Morphine PCA, Morphine (Intravenous patient-controlled analgesia)
3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 10 syntheses or guidelines pooled it, 144 citations in OpenAlex.

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  20. Impact of age on PUAL as an indicator of opioid effect in adult subjects.Journal of clinical monitoring and computing · 2026
    Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Alan David KayeDepartment of Anesthesiology, LSU Health Sciences Center, New Orleans, LA, USA.
Richard D UrmanDepartment of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Yury RappaportDepartment of Anesthesiology, LSU Health Shreveport, LA, USA.
Harish SiddaiahDepartment of Anesthesiology, LSU Health Shreveport, LA, USA.
Elyse M CornettDepartment of Anesthesiology, LSU Health Sciences Center, New Orleans, LA, USA.
Kumar BelaniDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Orlando J SalinasDepartment of Anesthesiology, LSU Health Sciences Center, New Orleans, LA, USA.
Charles J FoxDepartment of Anesthesiology, LSU Health Shreveport, LA, USA.
Louisiana State University Health Sciences Center Shreveport · USLouisiana State University Health Sciences Center New Orleans · USBrigham and Women's Hospital · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhanced recovery after surgery protocols are multimodal perioperative care pathways designed to achieve early recovery in patients after surgical procedures by defining and maintaining preoperative organ function and minimizing the profound stress response following surgery. Enhanced recovery protocols have primarily been studied for major abdominal surgeries, however, the knowledge acquired from studying these protocols has facilitated treating patients in ambulatory settings. The key components of enhanced recovery protocols include preoperative counseling, preoperative nutrition, altering the standard perioperative fasting guidelines, and the value of carbohydrate loading up to 2 hours preoperatively, standardized analgesic, and anesthetic regimens (epidural and nonopioid analgesia) and early mobilization. A PubMed search was performed with the following key words: multimodal analgesia, enhanced recovery, ambulatory care, pain management, and opioids. We discuss the use of enhanced recovery protocols and multimodal pain care plans in the ambulatory setting.

Indexed as

Ambulatory careenhanced recoverymultimodal analgesiaopioidspain management

Identifiers

PMID31142958
PMCPMC6515722
OpenAlexW2950460149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.