Evidence map›Paper›PMID 31142944›Full record

ArticleIndian journal of pharmacology

Change in antiepileptic drug prescription patterns for pregnant women with epilepsy over the years: Impact on pregnancy and fetal outcomes.

Ramandeep Bansal, Vanita Suri, Seema Chopra, Neelam Aggarwal, Pooja Sikka, Subhas Chandra Saha, Parampreet Singh Kharbanda, Praveen Kumar

Open access · greenAbstract read
In one paragraph

Article in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ramandeep BansalDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vanita SuriDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Seema ChopraDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Neelam AggarwalDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Pooja SikkaDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Subhas Chandra SahaDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Parampreet Singh KharbandaDepartment of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Praveen KumarDepartment of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS AND

objectivesThe objectives of the study were: (1) to determine if there is a change in pattern of antiepileptic drug (AED) prescription during pregnancy in women with epilepsy (WWE) attending a tertiary care institute in North India and (2) to determine if change in AED prescription pattern has resulted in improved fetal and maternal outcomes in WWE. PATIENTS AND

methodsThe current study was a retrospective analysis of records of WWE attending a medical and surgical disorder clinic of obstetrics and gynecology department of a tertiary care teaching hospital in North India. We retrospectively collected data of all the patients during the 5-year period from 2011 to 2015 (Group A) (

resultsThere was significantly higher use of (i) levetiracetam (LEV) in Group A compared to Group B when women on monotherapy were compared (

conclusionAlthough there is an increase in the use of newer AEDs in WWE during pregnancy in North Indian population, it has not resulted in improved maternal and fetal outcomes. (2) to determine if change in AED prescription pattern has resulted in improved fetal and maternal outcomes in WWE.

Indexed as

Practice Patterns, Physicians'Abnormalities, Drug-InducedAdultAnticonvulsantsBirth WeightCesarean SectionEpilepsyFemaleFetusHumansInfant, NewbornInfant, Small for Gestational AgePregnancyStillbirthYoung AdultAnticonvulsantsAntiepileptic drugsfetal and maternal outcomeswomen with epilepsy

Identifiers

PMID31142944
PMCPMC6533923
OpenAlexW2945369232

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.