ArticleIndian journal of psychiatry
Catechol-O-Methyltransferase Val158Met and brain-derived neurotrophic factor Val66Met gene polymorphisms in paraphilic sexual offenders.
Article in Indian journal of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed, 4 citations in OpenAlex.
- Mechanism of Catechol-O-methyltransferase Regulating Orofacial Pain Induced by Tooth Movement.BioMed research international · 2021Article
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5 authors at 1 institution in 1 country.
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Abstract
backgroundChild sexual abuse (CSA) is an important problem worldwide. The reason of sex abuse is considered as multifactorial. Genetic contribution reported by recent studies is a significant evidence for this pathologic behavior. Catechol-O-Methyltransferase (COMT) is an enzyme in the metabolic inactivation of catecholamine and substances containing catecholamines such as dopamine, epinephrine, and norepinephrine.
aimThis study aims to examine SETTINGS AND
designThis was a case-control study. MATERIALS AND
methodsSeventy paraphilic child sexual abuser patients and seventy age- and gender-matched healthy controls participated in this study.
resultsCOMT Val158Met genotype frequencies were determined as GG 31.4%, GA 45.7%, and AA 22.9% in patients; GG 24.3%, GA 45.7%, and AA 8.6% in controls; and exhibited a positive relationship between the groups (
conclusionsThis research investigated
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