Evidence map›Paper›PMID 31142763›Full record

ArticleScientific reports2019

Therapeutic potential of coenzyme Q

Kang Luo, Ji Hyun Yu, Yi Quan, Yoo Jin Shin, Kyung Eun Lee, Hong Lim Kim, Eun Jeong Ko, Byung Ha Chung, Sun Woo Lim, Chul Woo Yang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Coenzyme QMetabolic brain disease · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Tacrolimus and diabetic rodent models.Pharmacological reports : PR · 2025
    Review
  7. Article
  8. Review
  9. Understanding coenzyme Q.Physiological reviews · 2024
    Review
  10. The Scavenging Activity of Coenzyme QInternational journal of molecular sciences · 2024
    Article
  11. Article
  12. Article
  13. Research Progress of Coenzyme Q in Diabetes Mellitus and Its Common Complications.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  14. Article
  15. Article
  16. Anti-Oxidative Therapy in Islet Cell Transplantation.Antioxidants (Basel, Switzerland) · 2022
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Kang LuoConvergent Research Consortium for Immunologic Disease, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-4616-9955
Ji Hyun YuDepartment of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Korea.
Yi QuanConvergent Research Consortium for Immunologic Disease, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Republic of Korea.
Yoo Jin ShinConvergent Research Consortium for Immunologic Disease, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Republic of Korea.
Kyung Eun LeeAdvanced Analysis Center, Korea Institute of Science and Technology, Seoul, Korea.
Hong Lim KimIntegrative Research Support Center, The Catholic University of Korea School of Medicine, Seoul, Republic of Korea.
Eun Jeong KoConvergent Research Consortium for Immunologic Disease, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Republic of Korea.
Byung Ha ChungConvergent Research Consortium for Immunologic Disease, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-0048-5717
Sun Woo LimConvergent Research Consortium for Immunologic Disease, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Republic of Korea. swlim@catholic.ac.kr.
Chul Woo YangConvergent Research Consortium for Immunologic Disease, Seoul St. Mary's Hospital, The Catholic University of Korea School of Medicine, Seoul, Republic of Korea.
The Catholic University of Korea Seoul St. Mary's Hospital · KRCatholic University of Korea · KRKorean Association Of Science and Technology Studies · KRSt Mary's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that oxidative stress induced by long-term tacrolimus treatment impairs mitochondrial function in pancreatic beta cells. In this study, we aimed to investigate the therapeutic potential of coenzyme Q

Indexed as

AnimalsAntioxidantsApoptosisDiabetes Mellitus, ExperimentalHumansInsulinInsulin-Secreting CellsMitochondriaOxidative StressRatsReactive Oxygen SpeciesTacrolimusUbiquinoneAntioxidantscoenzyme Q10InsulinReactive Oxygen SpeciesTacrolimusUbiquinone

Identifiers

PMID31142763
PMCPMC6541596
OpenAlexW2947271876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.