Evidence map›Paper›PMID 31142670›Full record

ArticleJournal of virology2019

Kaposi Sarcoma-Associated Herpesvirus Glycoprotein H Is Indispensable for Infection of Epithelial, Endothelial, and Fibroblast Cell Types.

Murali Muniraju, Lorraine Z Mutsvunguma, Joslyn Foley, Gabriela M Escalante, Esther Rodriguez, Romina Nabiee, Jennifer Totonchy, David H Mulama, Joshua Nyagol, Felix Wussow and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Article
  9. Virus-like Particle (VLP) Vaccines for Cancer Immunotherapy.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Lack of CD8Oncotarget · 2020
    Article
  16. Article
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Murali MunirajuDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Lorraine Z MutsvungumaDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Joslyn FoleyDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Gabriela M EscalanteDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Esther RodriguezDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Romina NabieeChapman University, School of Pharmacy, Irvine, California, USA.
Jennifer TotonchyChapman University, School of Pharmacy, Irvine, California, USA.
David H MulamaDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Joshua NyagolDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Felix WussowDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Anne K BarasaDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA.
Michael BrehmProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Javier Gordon OgemboDepartment of Immuno-Oncology, Beckman Research Institute of City of Hope, Duarte, California, USA jogembo@coh.org.
City of Hope · USBeckman Research InstituteChapman University · USUniversity of Massachusetts Chan Medical School · USUniversity of Nairobi · KE

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI XIWEI WU · 1985 to 2026
$86.3M
Unmasking the roles of KSHV glycoproteins in virus entry and vaccine developmentK01CA184388 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI OGEMBO, JAVIER GORDON · 2014 to 2018
$536k
NCI NIH HHS K01 CA184388NCI NIH HHS P30 CA033572
6 · The paper itself

Abstract

Kaposi sarcoma-associated herpesvirus (KSHV) is an emerging pathogen and is the causative infectious agent of Kaposi sarcoma and two malignancies of B cell origin. To date, there is no licensed KSHV vaccine. Development of an effective vaccine against KSHV continues to be limited by a poor understanding of how the virus initiates acute primary infection

Indexed as

Viral TropismEndothelial CellsEpithelial CellsFibroblastsGenome, ViralGenomicsHerpesviridae InfectionsHerpesvirus 8, HumanHumansMutationViral Envelope ProteinsVirionVirus Internalizationglycoprotein H, human herpesvirus 8Viral Envelope ProteinsB cellendothelialepithelialfibroblastglycoprotein HinfectionKaposi sarcoma-associated herpesvirusmutationtropismviral entry

Identifiers

PMID31142670
PMCPMC6675886
OpenAlexW2945709947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.