Evidence map›Paper›PMID 31142588›Full record

ArticleThe Journal of experimental medicine2019

TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis.

Lisa A Mielke, Yang Liao, Ella Bridie Clemens, Matthew A Firth, Brigette Duckworth, Qiutong Huang, Francisca F Almeida, Michael Chopin, Hui-Fern Koay, Carolyn A Bell and 15 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Tcf-1 promotes genomic instability and T cell transformation in response to aberrant β-catenin activation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. TCF1 in T cell immunity: a broadened frontier.Nature reviews. Immunology · 2022
    Review
  12. Review
  13. Article
  14. TCF-1 controls TNature immunology · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 6 institutions in 2 countries.

Lisa A MielkeWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0002-9522-9320
Yang LiaoWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0002-9746-2839
Ella Bridie ClemensDepartment of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.
Matthew A FirthWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Brigette DuckworthWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Qiutong HuangWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Francisca F AlmeidaWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0001-6632-7610
Michael ChopinWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0001-8812-2763
Hui-Fern KoayDepartment of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.ORCID 0000-0002-3236-9609
Carolyn A BellDepartment of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, Australia.ORCID 0000-0001-6529-5426
Soroor Hediyeh-ZadehWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0001-7513-6779
Simone L ParkDepartment of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.ORCID 0000-0003-1507-0864
Dinesh RaghuOlivia Newton-John Cancer Research Institute and La Trobe University School of Cancer Medicine, Heidelberg, Australia.ORCID 0000-0002-8960-6222
Jarny ChoiDepartment of Anatomy and Neuroscience, University of Melbourne, Parkville, Australia.ORCID 0000-0002-7788-8867
Tracy L PutoczkiWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0003-1639-4932
Philip D HodgkinWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Ashley E FranksDepartment of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, Australia.ORCID 0000-0003-1664-6060
Laura K MackayDepartment of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.ORCID 0000-0002-8496-6632
Dale I GodfreyDepartment of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.ORCID 0000-0002-3009-5472
Melissa J DavisWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.
Hai-Hui XueDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA.ORCID 0000-0002-9163-7669
Vanessa L BryantWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0002-4697-7410
Katherine KedzierskaDepartment of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.ORCID 0000-0001-6141-335X
Wei ShiWalter and Eliza Hall Institute of Medical Research, Parkville, Australia.ORCID 0000-0003-1182-7735
Gabrielle T BelzWalter and Eliza Hall Institute of Medical Research, Parkville, Australia belz@wehi.edu.au.ORCID 0000-0002-9660-9587
The University of Melbourne · AULa Trobe University · AUAustralian Research Council · AUThe Royal Melbourne Hospital · AUUniversity of Iowa · USWalter and Eliza Hall Institute of Medical Research · AU

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
6 · The paper itself

Abstract

Interleukin (IL)-17-producing CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesChromatinChromatin Immunoprecipitation SequencingFlow CytometryHepatocyte Nuclear Factor 1-alphaHumansInterleukin-17Lipid MetabolismLymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutNuclear Receptor Subfamily 1, Group F, Member 3Proto-Oncogene Proteins c-mafT-Lymphocyte SubsetsChromatinHepatocyte Nuclear Factor 1-alphaHnf1a protein, mouseInterleukin-17Maf protein, mouseNuclear Receptor Subfamily 1, Group F, Member 3Proto-Oncogene Proteins c-maf

Identifiers

PMID31142588
PMCPMC6605755
OpenAlexW2947572413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.