ArticleBMJ open2019
Five-year prognosis and impact of adolescent knee pain: a prospective population-based cohort study of 504 adolescents in Denmark.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02873143 (5 Year Follow-up of Adolescents With Knee Pain - a Prospective Cohort Study of 504 Adolescents), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
5 Year Follow-up of Adolescents With Knee Pain - a Prospective Cohort Study of 504 Adolescents
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Exploring the Pain in Patellofemoral Pain: A Systematic Review and Meta-Analysis Examining Signs of Central Sensitization.Journal of athletic training · 2021Pooled it
- Adolescent perspectives on participating in a feasibility trial investigating shoe inserts for patellofemoral pain.Journal of foot and ankle research · 2022Trial
- HAPPi Kneecaps! A double-blind, randomised, parallel group superiority trial investigating the effects of sHoe inserts for adolescents with patellofemoral PaIn: phase II feasibility study.Journal of foot and ankle research · 2021Trial
- Trial
- Patellofemoral joint forces during running are not different between adolescents with and without patellofemoral pain-a cross-sectional study.Frontiers in sports and active living · 2026Article
- Observational
- Parental opioid prescriptions and the risk of opioid use in adolescents and young adults: The HUNT Study linked with prescription registry data.PLoS medicine · 2025Article
- Single-bundle vs. double-bundle isolated posterior cruciate ligament reconstruction: a retrospective cohort study on time to work and functional outcomes.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Expert opinion on heat therapy for teenagers' musculoskeletal pain management.Annals of translational medicine · 2024Review
- Prevalence of Abnormalities and Normal Variants in the Adolescent Knee on MRI in a Population-Based Cohort of 3800 Knees.The American journal of sports medicine · 2024Article
- Translation, cross-cultural adaptation and reliability of the International Knee Documentation Committee (IKDC) subjective knee form and the tampa scale for kinesiophobia (TSK) into Hebrew.Archives of orthopaedic and trauma surgery · 2023Article
- Exploring User Visions for Modeling mHealth Apps Toward Supporting Patient-Parent-Clinician Collaboration and Shared Decision-making When Treating Adolescent Knee Pain in General Practice: Workshop Study.JMIR human factors · 2023Article
- Flat flexible school shoes for adolescents with patellofemoral pain: a randomised, assessor-blinded, parallel-group feasibility trial.BMJ open sport & exercise medicine · 2023Article
- Protocol for a randomised, assessor-blinded, parallel group feasibility trial of flat flexible school shoes for adolescents with patellofemoral pain.Journal of foot and ankle research · 2022Article
- Risk factors for the occurrence and protraction of patellar and patellar tendon pain in children and adolescents: a prospective cohort study of 3 years.BMC musculoskeletal disorders · 2022Article
- Bio-psycho-social characteristics and impact of musculoskeletal pain in one hundred children and adolescents consulting general practice.BMC primary care · 2022Observational
- Test-retest reliability and agreement of lower-extremity kinematics captured in squatting and jumping preschool children using markerless motion capture technology.Frontiers in digital health · 2022Article
- Development and validation of the Sorting non-trauMatIc adoLescent knEe pain (SMILE) tool - a development and initial validation study.Pediatric rheumatology online journal · 2021Article
- The Role of Sleep in the Transition from Acute to Chronic Musculoskeletal Pain in Youth-A Narrative Review.Children (Basel, Switzerland) · 2021Review
- Musculoskeletal pain distribution in 1,000 Danish schoolchildren aged 8-16 years.Chiropractic & manual therapies · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesInvestigate the prognosis of adolescent knee pain, and evaluate its impact on health, care-seeking and career choices 5 years later.
designPre-registered, prospective cohort study.
settingPopulation-based cohort initiated in school setting.
participantsFrom a cohort of 2200 adolescents aged 15-19 years in 2011, 504 reported knee pain on at least a monthly basis, and were followed prospectively in this cohort study, together with 252 controls who did not have knee pain in 2011.
main outcome measuresOutcomes included the Pain and Symptoms subscales from the Knee injury and Osteoarthritis Outcome Score (KOOS), pain intensity measured with a Numeric Rating Scale, pain frequency, knee-related and health-related quality of life, sports participation, physical activity level, KOOS subscales: Function and Sport/recreation, quality of sleep, healthcare consultations, treatments received for their knee pain, the use of painkillers and impact on choice of job or career.
resultsAt follow-up, 358 (71.0%) from the knee pain group and 182 (72.2%) from the control group responded. Of note, 40.5% (95% CI: 35.4% to 45.6%) from the knee pain group reported knee pain 5 years later which was frequent and intense compared with 13.2% (95% CI: 8.2 to 18.1) of the control group. Those from the knee pain group still suffering from knee pain reported poorer physical health (13 points worse on KOOS Function and 30 points worse on KOOS Sport/recreation), stopped or reduced their sports participation because of knee pain (60%), reported worse sleep quality and worse knee-related and general quality of life. In terms of health behaviours, those still with knee pain reported more healthcare consultations. One-third used pain killers regularly, and 15% (95% CI: 12% to 20%) reported that knee pain influenced their choice of job or career.
conclusionFour out of every 10 adolescents with knee pain still experienced frequent and intense knee pain 5 years later, severe enough to impact health, health behaviours and career choices. TRAIL REGISTRATION NUMBER: NCT02873143.
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Registered trials
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