Evidence map›Paper›PMID 31142499›Full record

ReviewClinical microbiology reviews2019

Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface.

Sankalp Malhotra, Don Hayes, Daniel J Wozniak

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 307 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
307citing papers in PubMed, 1 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

307 citing papers in PubMed, 1 synthesis or guideline pooled it, 503 citations in OpenAlex.

  1. Pooled it
  2. Microenvironment shapesiScience · 2026
    Article
  3. Review
  4. A genome-wide screen inJournal of bacteriology · 2026
    Article
  5. Review
  6. Infection and immunity · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review

247 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sankalp MalhotraDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA.
Don HayesThe Ohio State University College of Medicine, Columbus, Ohio, USA.
Daniel J WozniakThe Ohio State University College of Medicine, Columbus, Ohio, USA Daniel.Wozniak@osumc.edu.
The Ohio State University · USNationwide Children's Hospital · US

Funding

Revisiting alginate paradigmsR01AI134895 · NIAID · OHIO STATE UNIVERSITY · PI WOZNIAK, DANIEL J · 2018 to 2022
$2.5M
Pseudomonas biofilms and immunityR01AI097511 · NIAID · OHIO STATE UNIVERSITY · PI WOZNIAK, DANIEL J · 2013 to 2017
$1.9M
The Ohio State University Center for Clinical and Translational ScienceTL1TR001069 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$763k
NCATS NIH HHS TL1 TR001069NIAID NIH HHS R01 AI097511NIAID NIH HHS R01 AI134895
6 · The paper itself

Abstract

In human pathophysiology, the clash between microbial infection and host immunity contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this phenomenon, wherein a dysfunctional, hyperinflammatory immune response combined with chronic pulmonary infections wreak havoc upon the airway, leading to a disease course of substantial morbidity and shortened life span.

Indexed as

Cystic FibrosisHost-Pathogen InteractionsHumansPseudomonas aeruginosaPseudomonas InfectionsVirulence FactorsVirulence Factorsairwayantimicrobial peptidescystic fibrosisinflammationinnate immunitylung infectionreactive oxygen speciesROS

Identifiers

PMID31142499
PMCPMC6589863
OpenAlexW2947765278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.