Evidence map›Paper›PMID 31142488›Full record

ArticleBMJ case reports2019

Atypical presentation of necrotising autoimmune myopathy.

Oyintayo Ajiboye, Michelle Manesh, Nisar Asmi, Benjamin Mba

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Oyintayo AjiboyeMedicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA.
Michelle ManeshRosalind Franklin University of Medicine and Science, North Chicago, Illinois, USA.
Nisar AsmiMedicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA.
Benjamin MbaMedicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA.
John H. Stroger, Jr. Hospital of Cook County · USRosalind Franklin University of Medicine and Science · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Necrotising autoimmune myopathy (NAM) is characterised by a common phenotype of profound symmetrical proximal muscle weakness, elevated creatine kinase levels, irritable myopathy on electromyography and histological findings of myocyte necrosis and regeneration without remarkable inflammation. NAM is associated with autoimmune antibodies including anti-3-hydroxy-3-methylglutaryl-coenzyme receptor, which is strongly associated with statin use. We report a case of statin-associated NAM with an atypical presentation of severe oropharyngeal dysphagia and no remarkable proximal muscle weakness at initial presentation but with rapid progression to severe quadriparesis in weeks. This case expands the spectrum of presentation patterns of this rare disease and highlights the need for a high index of suspicion in patients with a remote history of statin use.

Indexed as

AgedAutoantibodiesAutoimmune DiseasesDeglutition DisordersDiagnosis, DifferentialFatal OutcomeHumansMaleMuscle Fibers, SkeletalMuscle WeaknessMyositisNecrosisRare DiseasesAutoantibodiesconnective tissue diseasedrugs: musculoskeletal and joint diseasesmusculoskeletal syndromes

Identifiers

PMID31142488
PMCPMC6557363
OpenAlexW2947960402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.