Evidence map›Paper›PMID 31142356›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2019

Comparison of diffusion kurtosis imaging versus diffusion weighted imaging in predicting the recurrence of early stage single nodules of hepatocellular carcinoma treated by radiofrequency ablation.

Zhen-Guo Yuan, Zong-Ying Wang, Meng-Ying Xia, Feng-Zhi Li, Yao Li, Zhen Shen, Xi-Zhen Wang

Open access · goldAbstract readComparative Study
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhen-Guo YuanShandong Medical Imaging Research Institute Affiliated to Shandong University, Jinan, 250021, People's Republic of China.
Zong-Ying WangMedical Imaging Center of the Affiliated Hospital, Weifang Medical University, Weifang, 261053, People's Republic of China.
Meng-Ying XiaShandong Medical Imaging Research Institute Affiliated to Shandong University, Jinan, 250021, People's Republic of China.
Feng-Zhi LiMedical Imaging Center of the Affiliated Hospital, Weifang Medical University, Weifang, 261053, People's Republic of China.
Yao LiShandong Medical Imaging Research Institute Affiliated to Shandong University, Jinan, 250021, People's Republic of China.
Zhen ShenMedical Imaging Center of the Affiliated Hospital, Weifang Medical University, Weifang, 261053, People's Republic of China.
Xi-Zhen WangMedical Imaging Center of the Affiliated Hospital, Weifang Medical University, Weifang, 261053, People's Republic of China. wangxizhen@wfmc.edu.cn.ORCID http://orcid.org/0000-0003-0993-1170
Weifang Medical University · CNShandong University · CN

Funding

Key research and development program of shandong province GG201710080117National Natural Science Foundation of China 81641074,81171303,30470518,8177182Natural Science Foundation of Shandong Province ZR2009CL046,ZR2010HQ029,ZR2016HL40,ZR2017MH037Project of Medicine  and Health Development Plan of Shandong Province 2011HW067Scientific research award fund for outstanding young and middle-aged scientists in shandong province BS2012YY038Scientific research program of colleges and universities in shandong province J18KA288Shandong province medical and health science and technology development plan 2011WSB29009,2011HW067,2017WS408,2017WS579Shandong province science and technology development projection 2012 YD18064Shandong  Provincial Natural Science Foundation of China ZR2013HM071Weifang science and technology development project 2017YX054
6 · The paper itself

Abstract

objectiveThis study aimed to compare the diffusion kurtosis imaging (DKI) versus diffusion weighted imaging (DWI) in predicting the recurrence of early stage single nodules of hepatocellular carcinoma (HCC) treated by radiofrequency ablation (RFA). MATERIALS AND

methodsA retrospective analysis of 107 patients with early stage single nodules of HCC was performed, all patients treated by RFA. Recurrence rate of HCC was recorded after a median follow-up of 36 months. During follow-up, the data of magnetic resonance imaging (MRI), DWI and DKI were obtained in multiple time points. The predictive values of DWI and DKI were analyzed using ROC curves.

resultsThe overall recurrence rate was 66.3% (71/107). The sensitivity, specificity, and AUC for ADC, MD and MK after RFA (78.6, 73.3% and 0.842; 85.7, 83.3% and 0.839; 85.7, 96.7% and 0.956) were higher than before RFA (44.3, 53.3% and 0.560; 51.2, 56.7% and 0.543; 43.6, 67.3% and 0.489). The sensitivity, specificity, and AUC for MK after RFA were 85.7, 96.7%, and 0.956, respectively, which were significantly greater than those of ADC (78.6, 73.3% and 0.842; P < 0.05) and MD (85.7, 83.3% and 0.839).

conclusionsThe prediction efficacy of DKI for the recurrence of early stage single nodules of HCC was better than that of DWI. And, MK was the most sensitive predictor among the DKI.

Indexed as

Radiofrequency AblationAdultAgedCarcinoma, HepatocellularDiffusion Tensor ImagingFemaleHumansLiver NeoplasmsMaleMiddle AgedROC CurveDiffusion kurtosis imagingDiffusion weighted imagingHepatocellular carcinomaRadiofrequency ablation

Identifiers

PMID31142356
PMCPMC6542145
OpenAlexW2947857230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.