Evidence map›Paper›PMID 31142304›Full record

ArticleBMC veterinary research2019

In vitro antiviral activity of fifteen plant extracts against avian infectious bronchitis virus.

Raimundas Lelešius, Agneta Karpovaitė, Rūta Mickienė, Tomas Drevinskas, Nicola Tiso, Ona Ragažinskienė, Loreta Kubilienė, Audrius Maruška, Algirdas Šalomskas

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Pooled it
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    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Raimundas LelešiusInstitute of Microbiology and Virology, Veterinary Faculty, Lithuanian University of Health Sciences, Kaunas, Lithuania. raimundas.lelesius@lsmuni.lt.ORCID http://orcid.org/0000-0001-5007-6853
Agneta KarpovaitėDepartment of Veterinary Pathobiology, Veterinary Faculty, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Rūta MickienėInstrumental Analysis Open Access Centre, Vytautas Magnus University, Kaunas, Lithuania.
Tomas DrevinskasInstrumental Analysis Open Access Centre, Vytautas Magnus University, Kaunas, Lithuania.
Nicola TisoInstrumental Analysis Open Access Centre, Vytautas Magnus University, Kaunas, Lithuania.
Ona RagažinskienėSector of Medicinal Plants, Kaunas Botanical Garden of Vytautas Magnus University, Kaunas, Lithuania.
Loreta KubilienėFaculty of Pharmacy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Audrius MaruškaInstrumental Analysis Open Access Centre, Vytautas Magnus University, Kaunas, Lithuania.
Algirdas ŠalomskasDepartment of Veterinary Pathobiology, Veterinary Faculty, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Vytautas Magnus University · LTLithuanian University of Health Sciences · LT

Funding

Lietuvos Mokslo Taryba MIP-065/2015
6 · The paper itself

Abstract

backgroundAvian infectious bronchitis (IB) is a disease that can result in huge economic losses in the poultry industry. The high level of mutations of the IB virus (IBV) leads to the emergence of new serotypes and genotypes, and limits the efficacy of routine prevention. Medicinal plants, or substances derived from them, are being tested as options in the prevention of infectious diseases such as IB in many countries. The objective of this study was to investigate extracts of 15 selected medicinal plants for anti-IBV activity.

resultsExtracts of S. montana, O. vulgare, M. piperita, M. officinalis, T. vulgaris, H. officinalis, S. officinalis and D. canadense showed anti-IBV activity prior to and during infection, while S. montana showed activity prior to and after infection. M. piperita, O. vulgare and T. vulgaris extracts had > 60 SI. In further studies no virus plaques (plaque reduction rate 100%) or cytopathogenic effect (decrease of TCID

conclusionsMany extracts of plants acted against IBV prior to and during infection, but the most effective were those of M. piperita, T. vulgaris and D. canadense .

Indexed as

Plants, MedicinalAnimalsAntiviral AgentsChlorocebus aethiopsInfectious bronchitis virusMicrobial Sensitivity TestsPlant ExtractsReal-Time Polymerase Chain ReactionVero CellsViral Plaque AssayAntiviral AgentsPlant ExtractsAntiviral activityAvian infectious bronchitisPlant extracts

Identifiers

PMID31142304
PMCPMC6540435
OpenAlexW2947837155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.