Observational studyJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020
Contrast leakage distant from the hematoma in patients with spontaneous ICH: A 7 T MRI study.
Observational study in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- CSF enhancement on post-contrast fluid-attenuated inversion recovery images; a systematic review.NeuroImage. Clinical · 2020Pooled it
- The effect of minimally invasive intracerebral haematoma evacuation on early perihaematomal oedema formation.European stroke journal · 2026Article
- Cortical Cerebral Microinfarcts in Spontaneous Intracerebral Hemorrhage on 3T and 7T MRI.Neurology · 2025Observational
- Location and Timing of Recurrent, Nontraumatic Intracerebral Hemorrhage.JAMA neurology · 2025Article
- Evaluating the role of 7-Tesla magnetic resonance imaging in neurosurgery: Trends in literature since clinical approval.World journal of radiology · 2024Article
- Long-term outcome of cerebral amyloid angiopathy-related hemorrhage.CNS neuroscience & therapeutics · 2022Observational
- Normal cerebrospinal fluid concentrations of PDGFRβ in patients with cerebral amyloid angiopathy and Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Diffusion-Weighted Lesions After Intracerebral Hemorrhage: Associated MRI Findings.Frontiers in neurology · 2022Article
- 7T dynamic contrast-enhanced MRI for the detection of subtle blood-brain barrier leakage.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2021Article
- Differences in cerebral small vessel disease magnetic resonance imaging markers between lacunar stroke and non-Lobar intracerebral hemorrhage.European stroke journal · 2021Article
- Galectin-9 Promotes Neuronal Restoration via Binding TLR-4 in a Rat Intracerebral Hemorrhage Model.Neuromolecular medicine · 2021Article
- RAB7L1 Participates in Secondary Brain Injury Induced by Experimental Intracerebral Hemorrhage in Rats.Journal of molecular neuroscience : MN · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disruption of the blood-brain barrier (BBB) might play a role in the pathophysiology of cerebral small vessel disease-related ICH. The aim of this study was to assess presence and extent of contrast agent leakage distant from the hematoma as a marker of BBB disruption in patients with spontaneous ICH. We prospectively performed 7 tesla MRI in adult patients with spontaneous ICH and assessed contrast leakage distant from the hematoma on 3D FLAIR images. Thirty-one patients were included (mean age 60 years, 29% women). Median time between ICH and MRI was 20 days (IQR 9-67 days). Seventeen patients (54%; seven lobar, nine deep, one infratentorial ICH) had contrast leakage, located cortical in 16 and cortical and deep in one patient. Patients with contrast leakage more often had lobar cerebral microbleeds (CMBs; 77%) than those without (36%; RR 2.5, 95% CI 1.1-5.7) and a higher number of lobar CMBs (patients with contrast leakage: median 2, IQR 1-8 versus those without: median 0, IQR 0-2;
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