Evidence map›Paper›PMID 31141985›Full record

ArticleGenes2019

Transcriptome Changes of Skeletal Muscle RNA-Seq Speculates the Mechanism of Postprandial Hyperglycemia in Diabetic Goto-Kakizaki Rats During the Early Stage of T2D.

Wenlu Zhang, Yuhuan Meng, Shuying Fu, Xingsong Li, Zixi Chen, Lizhen Huang, Hongli Du

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Characteristics of Gastric Microbiota in GK Rats with Spontaneous Diabetes: A Comparative Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wenlu ZhangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510000, China. zhang.wenlu@mail.scut.edu.cn.
Yuhuan MengSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510000, China. mengyh@scut.edu.cn.
Shuying FuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510000, China. 201610104915@mail.scut.edu.cn.
Xingsong LiSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510000, China. 201621034294@mail.scut.edu.cn.
Zixi ChenSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510000, China. bizic_chen@mail.scut.edu.cn.
Lizhen HuangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510000, China. Huanglzh@scut.edu.cn.
Hongli DuSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510000, China. hldu@scut.edu.cn.
South China University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address how skeletal muscle contributes to postprandial hyperglycemia, we performed skeletal muscle transcriptome analysis of diabetic Goto-Kakizaki (GK) and control Wistar rats by RNA sequencing (RNA-Seq). We obtained 600 and 1785 differentially expressed genes in GK rats compared to those Wistar rats at three and four weeks of age, respectively. Specifically,

Indexed as

AnimalsBlood GlucoseDiabetes Mellitus, Type 2Exome SequencingGene Expression RegulationHigh-Throughput Nucleotide SequencingHumansHyperglycemiaInsulinMuscle, SkeletalPhosphorylationRatsTranscriptomeBlood GlucoseInsulinGoto-Kakizaki (GK) ratspostprandial hyperglycemiaRNA-Seqskeletal muscletype 2 diabetes (T2D)

Identifiers

PMID31141985
PMCPMC6627578
OpenAlexW2947228100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.