Evidence map›Paper›PMID 31141932›Full record

ArticleCells2019

Analysis of Genetic Alterations in Tunisian Patients with Lung Adenocarcinoma.

Dhoha Dhieb, Imen Belguith, Laura Capelli, Elisa Chiadini, Matteo Canale, Sara Bravaccini, Ilhem Yangui, Ons Boudawara, Rachid Jlidi, Tahya Boudawara and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. The Current Roadmap of Lung Cancer Biology, Genomics and Racial Disparity.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Analysis of EGFR Mutation Status in Algerian Patients with Non-Small Cell Lung Cancer.Asian Pacific journal of cancer prevention : APJCP · 2021
    Article
  10. Cancer in Africa: The Untold Story.Frontiers in oncology · 2021
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Dhoha DhiebBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola 47014, Italy. dhoha.dhieb@gmail.com.
Imen BelguithLaboratory of Human Molecular Genetics, Faculty of Medicine of Sfax, University of Sfax, Sfax 3029, Tunisia. mayno87.ib@gmail.com.
Laura CapelliBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola 47014, Italy. laura.capelli@irst.emr.it.
Elisa ChiadiniBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola 47014, Italy. elisa.chiadini@irst.emr.it.
Matteo CanaleBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola 47014, Italy. matteo.canale@irst.emr.it.
Sara BravacciniBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola 47014, Italy. sara.bravaccini@irst.emr.it.
Ilhem YanguiDepartment of Respiratory and Sleep Diseases, CHU Hedi Chaker, Sfax 3029, Tunisia. ilhem.bouazizyangui@gmail.com.
Ons BoudawaraDepartment of Pathology, CHU Habib Bourguiba, Sfax 3029, Tunisia. annoussa1988@hotmail.com.
Rachid JlidiLaboratory of Anatomic Pathology, Sfax 3000, Tunisia. rachid.jlidi@gmail.com.
Tahya BoudawaraDepartment of Pathology, CHU Habib Bourguiba, Sfax 3029, Tunisia. tahya.sellami@rns.tn.
Daniele CalistriBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola 47014, Italy. daniele.calistri@irst.emr.it.
Leila Ammar KeskesLaboratory of Human Molecular Genetics, Faculty of Medicine of Sfax, University of Sfax, Sfax 3029, Tunisia. ammarkeskesl@gmail.com.
Paola UliviBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola 47014, Italy. paola.ulivi@irst.emr.it.
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITUniversity of Sfax · TNHopital Universitaire Habib Bourguiba · TNHopital Universitaire Hedi Chaker · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification of the mutations that drive lung cancer have furnished new targets for the treatment of non-small cell lung cancer (NSCLC) and led to the development of targeted therapies such as tyrosine kinase inhibitors that are used to combat the molecular changes promoting cancer progression. Furthermore, biomarkers identified from gene analysis can be used to detect early lung cancer, determine patient prognosis, and monitor response to therapy. In the present study we analyzed the molecular profile of seventy-three Tunisian patients with lung adenocarcinoma (LAD). Mutational analyses for

Indexed as

Genetic VariationAdenocarcinoma of LungAgedAnaplastic Lymphoma KinaseErbB ReceptorsFemaleHumansMaleMiddle AgedMutationProto-Oncogene Proteins p21(ras)SmokingTumor Suppressor Protein p53TunisiaALK protein, humanAnaplastic Lymphoma KinaseEGFR protein, humanErbB ReceptorsKRAS protein, humanProto-Oncogene Proteins p21(ras)Tumor Suppressor Protein p53ALKEGFRKRASlung adenocarcinomamolecular profilep53

Identifiers

PMID31141932
PMCPMC6627075
OpenAlexW2947181236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.