Evidence map›Paper›PMID 31141907›Full record

ArticleInternational journal of molecular sciences2019

Melatonin Reduces Excitability in Dorsal Root Ganglia Neurons with Inflection on the Repolarization Phase of the Action Potential.

Klausen Oliveira-Abreu, Nathalia Maria Silva-Dos-Santos, Andrelina Noronha Coelho-de-Souza, Francisco Walber Ferreira-da-Silva, Kerly Shamyra da Silva-Alves, Ana Carolina Cardoso-Teixeira, José Cipolla-Neto, José Henrique Leal-Cardoso

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Understanding daily rhythms in weakly electric fish: the role of melatonin on the electric behavior of Brachyhypopomus gauderio.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024
    Article
  6. Article
  7. Article
  8. Effects of Melatonin on Diabetic Neuropathy and Retinopathy.International journal of molecular sciences · 2021
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Klausen Oliveira-AbreuLaboratório de Eletrofisiologia, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil. klausenoliveira@gmail.com.ORCID 0000-0002-3522-670X
Nathalia Maria Silva-Dos-SantosLaboratório de Eletrofisiologia, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil. nathaliamsantos14@gmail.com.ORCID 0000-0003-4114-0176
Andrelina Noronha Coelho-de-SouzaLaboratório de Eletrofisiologia, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil. andrelinanoronha@gmail.com.ORCID 0000-0002-7357-0958
Francisco Walber Ferreira-da-SilvaLaboratório de Eletrofisiologia, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil. walberferreira@gmail.com.ORCID 0000-0003-2012-2040
Kerly Shamyra da Silva-AlvesLaboratório de Eletrofisiologia, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil. shamyrabio@gmail.com.ORCID 0000-0002-9542-0037
Ana Carolina Cardoso-TeixeiraLaboratório de Eletrofisiologia, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil. anacarolina.acct@gmail.com.ORCID 0000-0002-8675-7746
José Cipolla-NetoLaboratório de Neurobiologia, Instituto de Ciências Biomédicas 1, Universidade de São Paulo, São Paulo 05508-000, SP, Brasil. cipolla@icb.usp.br.ORCID 0000-0003-3748-3731
José Henrique Leal-CardosoLaboratório de Eletrofisiologia, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil. lealcard@gmail.com.ORCID 0000-0002-3972-1361
Universidade Estadual do Ceará · BRUniversidade de São Paulo · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 407449/2016-7Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico PR2-0101-00036.01.00/15 (Public notice 02/2015 (PRONEX)Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/50457-0
6 · The paper itself

Abstract

Melatonin is a neurohormone produced and secreted at night by pineal gland. Many effects of melatonin have already been described, for example: Activation of potassium channels in the suprachiasmatic nucleus and inhibition of excitability of a sub-population of neurons of the dorsal root ganglia (DRG). The DRG is described as a structure with several neuronal populations. One classification, based on the repolarizing phase of the action potential (AP), divides DRG neurons into two types: Without (N

Indexed as

Action PotentialsAnimalsCells, CulturedCentral Nervous System DepressantsGanglia, SpinalMaleMelatoninNeuronsRatsRats, WistarCentral Nervous System DepressantsMelatoninaction potentialdorsal root ganglionDRGexcitabilitymelatoninpassive electric properties

Identifiers

PMID31141907
PMCPMC6600424
OpenAlexW2947250959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.