Evidence map›Paper›PMID 31141888›Full record

ReviewCells2019

5',8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance.

Chryssostomos Chatgilialoglu, Carla Ferreri, Nicholas E Geacintov, Marios G Krokidis, Yuan Liu, Annalisa Masi, Vladimir Shafirovich, Michael A Terzidis, Pawlos S Tsegay

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Chemical Insights into Oxidative and Nitrative Modifications of DNA.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Biomimetic Ketone Reduction by Disulfide Radical Anion.Molecules (Basel, Switzerland) · 2021
    Article
  15. When UDG and hAPE1 Meet Cyclopurines. How (5'Molecules (Basel, Switzerland) · 2021
    Article
  16. Review
  17. Article
  18. The Influence of 5'Molecules (Basel, Switzerland) · 2021
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Chryssostomos ChatgilialogluIstituto per la Sintesi Organica e la Fotoreattività, Consiglio Nazionale delle Ricerche, Via P. Gobetti 101, 40129 Bologna, Italy. chrys@isof.cnr.it.
Carla FerreriIstituto per la Sintesi Organica e la Fotoreattività, Consiglio Nazionale delle Ricerche, Via P. Gobetti 101, 40129 Bologna, Italy. carla.ferreri@isof.cnr.it.
Nicholas E GeacintovDepartment of Chemistry, New York University, 31 Washington Place, New York, NY 10003-5180, USA. nicholas.geacintov@nyu.edu.
Marios G KrokidisInstitute of Nanoscience and Nanotechnology, N.C.S.R. "Demokritos", 15310 Agia Paraskevi Attikis, Greece. m.krokidis@inn.demokritos.gr.
Yuan LiuDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th Street, Miami, FL 33199, USA. yualiu@fiu.edu.
Annalisa MasiIstituto per la Sintesi Organica e la Fotoreattività, Consiglio Nazionale delle Ricerche, Via P. Gobetti 101, 40129 Bologna, Italy. annalisa.masi@isof.cnr.it.
Vladimir ShafirovichDepartment of Chemistry, New York University, 31 Washington Place, New York, NY 10003-5180, USA. vs5@nyu.edu.
Michael A TerzidisLaboratory of Chemical and Environmental Technology, Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. mterzidi@gmail.com.
Pawlos S TsegayBiochemistry Ph.D. Program, Florida International University, Miami, FL 33199, USA. ptseg001@fiu.edu.
Institute of Organic Synthesis and Photoreactivity · ITFlorida International University · USNew York University · USAristotle University of Thessaloniki · GRNational Centre of Scientific Research "Demokritos" · GR

Funding

Interplay between DNA repair mechanisms in human cells and extractsR01ES027059 · NIEHS · NEW YORK UNIVERSITY · PI SHAFIROVICH, VLADIMIR · 2016 to 2020
$1.8M
Recognition of Environmental Carcinogen-DNA lesions by NER ProteinsR01ES024050 · NIEHS · NEW YORK UNIVERSITY · PI GEACINTOV, NICHOLAS E · 2014 to 2018
$1.8M
Trinucleotide Repeat Instability via DNA Damage and RepairR01ES023569 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI LIU, YUAN · 2014 to 2018
$1.6M
NIEHS NIH HHS R01 ES023569NIEHS NIH HHS R01 ES024050NIEHS NIH HHS R01 ES027059
6 · The paper itself

Abstract

Purine 5',8-cyclo-2'-deoxynucleosides (cPu) are tandem-type lesions observed among the DNA purine modifications and identified in mammalian cellular DNA in vivo. These lesions can be present in two diasteroisomeric forms, 5'

Indexed as

DNA DamageAnimalsDNA RepairHumansOligonucleotidesPurinesReactive Oxygen SpeciesSmall Molecule LibrariesOligonucleotidesPurinesReactive Oxygen SpeciesSmall Molecule LibrariescancercyclopurinesDNA and RNA polymerasesDNA damagefree radicalsLC-MS/MSnucleotide excision repairreactive oxygen speciesxeroderma pigmentosum

Identifiers

PMID31141888
PMCPMC6628319
OpenAlexW2947923834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.