SynthesisPloS one2019
Molecular and serological surveys of canine distemper virus: A meta-analysis of cross-sectional studies.
Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recommendations on vaccination for Latin American small animal practitioners: a report of the WSAVA Vaccination Guidelines Group.The Journal of small animal practice · 2020Guideline
- Investigation of the canine distemper virus in dogs living at public kennels in Northern Brazil: validation of a detection assay.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Article
- Epidemiological, Clinical, and Molecular Insights into Canine Distemper Virus in the Mekong Delta Region of Vietnam.Viruses · 2025Article
- Multiplex one-step RT‒qPCR assays for simultaneous detection of AMDV, MEV and CDV.BMC veterinary research · 2025Article
- Immuno-chromatography based rapid detection of canine distemper in dogs and its comparison with RT-PCR.Veterinary research forum : an international quarterly journal · 2025Article
- Epitope mapping and a candidate vaccine design from canine distemper virus.Open veterinary journal · 2024Article
- Effect of maternally derived antibodies on two commercial vaccines in changes of serum antibody titres against distemper in puppies.Veterinary medicine and science · 2023Article
- Canine morbillivirus (CDV): a review on current status, emergence and the diagnostics.Virusdisease · 2022Review
- Critical Problems for Research in Animal Sheltering, a Conceptual Analysis.Frontiers in veterinary science · 2022Review
- First complete genome sequence and molecular characterization of Canine morbillivirus isolated in Central Brazil.Scientific reports · 2021Article
- Development of recombinase polymerase amplification assays for rapid and visual detection of canine distemper virus infecting giant panda.BMC veterinary research · 2021Article
- Higher Prevalence of Extended-Spectrum Cephalosporin-ResistantAntibiotics (Basel, Switzerland) · 2021Article
- Intake Vaccinations Reduced Signs of Canine Respiratory Disease During an Outbreak at an Animal Shelter.Frontiers in veterinary science · 2021Article
- Molecular characterization of canine coronaviruses: an enteric and pantropic approach.Archives of virology · 2021Article
- Seroprevalence and risk factors of canine distemper virus in the pet and stray dogs in Haa, western Bhutan.BMC veterinary research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCanine morbillivirus (canine distemper virus, CDV) persists as a serious threat to the health of domestic dogs and wildlife. Although studies have been conducted on the frequency and risk factors associated with CDV infection, there are no comprehensive data on the current epidemiological magnitude in the domestic dog population at regional and national levels. Therefore, we conducted a cross-sectional study and included our results in a meta-analysis to summarize and combine available data on the frequency and potential risk factors associated with CDV infection.
methodsFor the cross-sectional study, biological samples from dogs suspected to have canine distemper (CD) were collected and screened for viral RNA. Briefly, the PRISMA protocol was used for the meta-analysis, and data analyses were performed using STATA IC 13.1 software.
resultsCDV RNA was detected in 34% (48/141) of dogs suspected to have CD. Following our meta-analysis, 53 studies were selected for a total of 11,527 dogs. Overall, the pooled frequency of CDV positivity based on molecular and serological results were 33% (95% CI: 23-43) and 46% (95% CI: 36-57), respectively. The pooled subgroup analyses of clinical signs, types of biological samples, diagnostic methods and dog lifestyle had a wide range of CDV positivity (range 8-75%). Free-ranging dogs (OR: 1.44, 95% CI: 1.05-1.97), dogs >24 months old (OR: 1.83, 95% CI: 1.1-3) and unvaccinated dogs (OR: 2.92, 95% CI: 1.26-6.77) were found to be positively associated with CDV infection. In contrast, dogs <12 months old (OR: 0.36, 95% CI: 0.20-0.64) and dogs with a complete anti-CDV vaccination (OR: 0.18, 95% CI: 0.05-0.59) had a negative association.
conclusionConsidering the high frequency of CDV positivity associated with almost all the variables analyzed in dogs, it is necessary to immediately and continuously plan mitigation strategies to reduce the CDV prevalence, especially in determined endemic localities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.