Evidence map›Paper›PMID 31141541›Full record

SynthesisPloS one2019

The effect of lung recruitment maneuvers on post-operative pulmonary complications for patients undergoing general anesthesia: A meta-analysis.

Yu Cui, Rong Cao, Gen Li, Tianqing Gong, Yingyu Ou, Jing Huang

2 registry-linked trialsAbstract readMeta-Analysis
In one paragraph

Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06454305 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Comparative Effects of Active Cycle of Breathing Technique and Blow Bottle Technique to Prevent Post-operative Pulmonary Complications in Patients With Abdominal Surgeries Under General Anesthesia

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled44ConditionsAbdominal SurgeryArmsActive cycle of breathing technique, Blow Bottle Technique
NCT07462689 nacompletednot on this mapstarted 2020, after this paper: background citation

Comparison of Positive End-expiratory Pressure and Alveolar Recruitment Maneuver on Perioperative Oxygenation in Patients Undergoing Robotic Radical Prostatectomy: a Randomized Controlled Trial

TypeinterventionalSponsorIlsan Cha hospitalRan2020 to 2024Enrolled58ConditionsRobot-Assisted Radical ProstatectomyArmsPEEP group, PEEP + ARM group
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu CuiDepartment of Anesthesiology, Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan, China.ORCID 0000-0002-1481-9389
Rong CaoDepartment of Anesthesiology, Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan, China.
Gen LiDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Tianqing GongDepartment of Anesthesiology, Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan, China.
Yingyu OuDepartment of Anesthesiology, Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan, China.
Jing HuangDepartment of Anesthesiology, Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory function would be impaired during general anesthesia period. Researchers devoted their energies to finding effective strategies for protecting respiratory function. Low tidal volume, positive end-expiratory pressure (PEEP), and lung recruitment maneuvers (LRMs) were recommended for patients under mechanical ventilation. However, based on the current evidence, there was no consensus on whether LRMs should be routinely used for anesthetized patients with healthy lungs, and the benefits of them remained to be determined. MATERIALS AND

methodsTo evaluate the benefits of LRMs on patients undergoing surgery with general anesthesia, we searched relevant studies in PubMed, EMBASE, Ovid Medline and the Cochrane Library up to June 30, 2018. The primary outcome was postoperative pulmonary complications (PPCs).

resultsTwelve trials involving 2756 anesthetized patients were included. The results of our study showed a significant benefit of LRMs for reducing the incidence of PPCs (RR = 0.67; 95%CI, 0.49 to 0.90; P<0.05; Chi2 = 32.94, p for heterogeneity = 0.0005, I2 = 67%). After subgroup analyses, we found LRMs combining with lung protective ventilation strategy and sustained recruitment maneuvers were associated with reducing the occurrence of PPCs. The results also revealed that the use of LRMs improved PaO2/FiO2 in non-obese patients, but with extremely high heterogeneity (I2 = 95%).

conclusionAccording to the findings from contemporary meta-analysis, LRMs combining with lung protective ventilation strategy may have an association with decreasing in the incidence of PPCs and improvement of oxygenation on non-obese patients. However, the conclusions must be interpreted cautiously as the outcome may be influenced dramatically due to varied LRMs and ventilation patterns.

Indexed as

Anesthesia, GeneralFemaleHumansIntraoperative CareLungMalePositive-Pressure RespirationPostoperative ComplicationsPostoperative PeriodRespiration, ArtificialTidal Volume

Identifiers

PMID31141541
PMCPMC6541371

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.