Evidence map›Paper›PMID 31141516›Full record

ArticlePLoS medicine2019

The missed potential of CD4 and viral load testing to improve clinical outcomes for people living with HIV in lower-resource settings.

Peter D Ehrenkranz, Solange L Baptiste, Helen Bygrave, Tom Ellman, Naoko Doi, Anna Grimsrud, Andreas Jahn, Thokozani Kalua, Rose Kolola Nyirenda, Michael O Odo and 3 more

Abstract read
In one paragraph

Article in PLoS medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Exosome and virus infection.Frontiers in immunology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peter D EhrenkranzGlobal Health, Bill and Melinda Gates Foundation, Seattle, Washington, United States of America.ORCID 0000-0003-2028-4779
Solange L BaptisteInternational Treatment Preparedness Coalition, Gaborone, Botswana.
Helen BygraveMédecins Sans Frontières Access Campaign, Geneva, Switzerland.
Tom EllmanSouthern African Medical Unit, Médecins Sans Frontières, Cape Town, South Africa.
Naoko DoiClinton Health Access Initiative, Boston, Massachusetts, United States of America.
Anna GrimsrudHIV Programmes and Advocacy, International AIDS Society, Geneva, Switzerland.
Andreas JahnDepartment of HIV/AIDS, Malawi Ministry of Health, Lilongwe, Malawi.
Thokozani KaluaDepartment of HIV/AIDS, Malawi Ministry of Health, Lilongwe, Malawi.
Rose Kolola NyirendaDepartment of HIV/AIDS, Malawi Ministry of Health, Lilongwe, Malawi.
Michael O OdoDepartment of HIV/AIDS, Malawi Ministry of Health, Lilongwe, Malawi.
Pascale OndoaAfrican Society of Laboratory Medicine, Addis Ababa, Ethiopia.
Lara VojnovWorld Health Organization, Geneva, Switzerland.ORCID 0000-0003-0488-1012
Charles B HolmesCenter for Global Health and Quality, Georgetown University, Washington, DC, United States of America.ORCID 0000-0002-7924-6761

Funding

World Health Organization 001
6 · The paper itself

Abstract

In a Policy Forum, Peter Ehrenkranz and colleagues discuss the contribution of CD4 and viral load testing to outcomes for people with HIV in low- and middle-income countries.

Indexed as

CD4 Lymphocyte CountDeveloping CountriesGlobal HealthHIVViral LoadAnti-HIV AgentsHealth Care CostsHealth Services AccessibilityHIV InfectionsHumansPredictive Value of TestsPrognosisRisk FactorsAnti-HIV Agents

Identifiers

PMID31141516
PMCPMC6541248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.